What should I watch for?
Visit your doctor or health care professional for regular checks on your progress. This medicine can cause serious liver problems. Make sure you understand the risks for liver problems and how to identify the symptoms. If you have any questions, talk with your doctor or other health care provider.
Avoid alcoholic drinks while you are taking this medicine. Drinking alcohol during treatment with this medicine increases the risk of serious liver problems.
Antacids may reduce the absorption of this medicine. Doses of this medicine should be given at least 1 hour before taking antacids.
This medicine can color your urine, feces (stool), perspiration (sweat), tears, sputum, skin or saliva reddish-orange to reddish-brown. This color can last for as long as you take this medicine and is not a cause for alarm. This color in tears may permanently stain soft contact lenses. It is better not to wear soft contact lenses while you are taking this medicine.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
blood in the urine or stools
cough or hoarseness
coughing or vomiting blood
darkening of the skin
decreased frequency or amount of urine
difficulty in breathing and swallowing
fever with or without chills
general feeling of tiredness or weakness
increased blood pressure
loss of appetite
lower back or side pain
painful or difficult urination
persistent bleeding or oozing from puncture sites, mouth, or nose
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
skin itching, rash, or redness
sores, ulcers, or white spots on the lips or in the mouth
swelling of the face, ankles, fingers, hands, or lower legs
tightness in the chest
unusual bleeding or bruising
unusual tiredness or weakness
yellow eyes or skin
Incidence not known
Blistering, peeling, or loosening of the skin
bloody, severe, or watery diarrhea
cold, clammy skin
difficulty with speaking
fast, weak pulse
inability to move the arms, legs, or facial muscles
inability to speak
joint or muscle pain
pinpoint red spots on the skin
red skin lesions, often with a purple center
red, irritated eyes
sores, welting, blisters
unpleasant breath odor
unusual weight loss
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, pounding, or irregular heartbeat or pulse
full feeling in the upper abdomen or stomach
low blood pressure or slow pulse
pain in the upper abdomen or stomach
reddish-orange to reddish-brown color of the urine, stool, saliva, sputum, sweat, and tears
swelling around the eyes or face
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Feeling that others are watching you or controlling your behavior
feeling that others can hear your thoughts
feeling, seeing, or hearing things that are not there
severe mood or mental changes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.