The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Side effects below were reported in at least 5% of adults taking Prezista (darunavir) with ritonavir (Norvir) during clinical studies.
- Diarrhea
- Nausea
- Stomach pain
- Vomiting
- Headache
- Rash
Side effects below were reported in at least 5% of adults taking Tybost (cobicistat) with other HIV medications in clinical studies.
- Jaundice
- Rash
Prezcobix serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious liver problems: nausea, vomiting, not feeling hungry, pain in the right side of the stomach, yellowing of the whites of the eyes or skin, dark-colored urine, light-colored stool
- Severe allergic or skin reactions: facial swelling, hives, rash, itchy skin, blistering or peeling of skin, body aches, trouble breathing, fever
Source: DailyMed
The following Prezcobix side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
- Infection—fever, chills, cough, or sore throat
- Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
- Lipodystrophy—increased fat in the upper back or midsection, decreased fat in the face, arms, or legs
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Rash, fever, and swollen lymph nodes
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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