Skip to main content
Atazanavir

Atazanavir Side Effects

Ally Tsai, PharmDConnie Zheng, PharmD
Reviewed by Ally Tsai, PharmD, Connie Zheng, PharmD
Last reviewed on June 12, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Higher liver enzyme levels (44-49%)
  • Higher cholesterol levels (up to 25%)
  • Nausea (3-14%)
  • Yellowing of the skin or whites of the eyes (7-9%)
  • Headache (1-6%)
  • Vomiting (3-4%)
  • Belly pain (4%)
  • Nerve pain (4%)
  • Rash (3-7%)
  • Diarrhea (1-3%)

Please note: The side effects above were reported in adults taking this medication with other HIV ARVs. Side effects might differ in children.

Less Common Side Effects

  • Trouble sleeping
  • Dizziness
  • Fever
  • Feeling depressed

Atazanavir serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic and skin reactions: facial swelling, hives, rash, itchy skin, blistering or peeling of skin, body aches, trouble breathing
  • Serious liver problems: nausea, vomiting, not feeling hungry, pain in the right side of the stomach, yellowing of the whites of the eyes or skin, dark-colored urine, light-colored stool
  • Abnormal heart rhythm: chest pounding, trouble breathing, chest pain, feeling faint or lightheaded

Source: DailyMed

The following Atazanavir side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Bloating

blood in the urine

blurred vision

chest pain or discomfort

chills

clay-colored stools

constipation

dark urine

decreased appetite

diarrhea

dizziness or lightheadedness

dry mouth

fainting

fast heartbeat

fast, shallow breathing

fever

flushed, dry skin

fruit-like breath odor

gaseous abdominal or stomach pain

general feeling of discomfort

headache

hives, itching, or skin rash

increased hunger

increased thirst

increased urination

indigestion

irregular heartbeat

loss of appetite

loss of consciousness

muscle pain or cramping

nausea

pain in the groin or genitals

pain in the stomach, side, or abdomen, possibly radiating to the back

recurrent fever

severe nausea or vomiting

sharp back pain just below the ribs

sleepiness

slow or irregular heartbeat

stomach discomfort or fullness

sweating

swelling

tightness in the chest

trouble with breathing

unexplained weight loss

unpleasant breath odor

unusual tiredness or weakness

vomiting

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

cough, increased

discouragement

extra body fat

feeling sad or empty

irritability

loss of interest or pleasure

trouble concentrating

trouble sleeping

Less common

Burning, numbness, tingling, or painful sensations

difficulty with moving

muscle stiffness

pain

pain in the joints

unsteadiness or awkwardness

weakness in the arms, hands, legs, or feet

Incidence not known

Hair loss or thinning of the hair

rash with flat lesions or small raised lesions on the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

why trust our exports reliability shield

Why trust our experts?

Ally Tsai, PharmD
Reviewed by:
Ally Tsai, PharmD
Ally Tsai, PharmD, is a medication therapy management (MTM) pharmacist with 6 years of experience. As an MTM pharmacist, she helps people with complex medication regimens get the best results by conducting comprehensive medication reviews.
Connie Zheng, PharmD, is a drug information pharmacist at GoodRx and a licensed pharmacist in California. She has over 6 years of experience working in independent pharmacies.

Was this page helpful?