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Fosamprenavir

Fosamprenavir Side Effects

Ally Tsai, PharmDConnie Zheng, PharmD
Reviewed by Ally Tsai, PharmD, Connie Zheng, PharmD
Last reviewed on May 30, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Diarrhea (5-13%)
  • Higher levels of fats in the body (up to 11%)
  • Higher liver labs (6-8%)
  • Rash (3-8%)
  • Nausea (3-7%)

Please note: The side effects above include those reported by people who also took ritonavir (Norvir) with fosamprenavir (Lexiva) during clinical trials.

Less Common Side Effects

  • Vomiting
  • Belly pain
  • Feeling tired
  • Headache

Fosamprenavir serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reactions: facial swelling, hives, rash, itchy skin, welts, body aches, trouble breathing
  • Severe skin reactions: fever, cough, sore throat, body aches, peeling or blistering skin rash
  • Serious liver problems: nausea, vomiting, not feeling hungry, pain in the right side of the stomach, yellowing of the whites of the eyes or skin, dark-colored urine, light-colored stool

Source: DailyMed

The following Fosamprenavir side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Hemolytic anemia—unusual weakness or fatigue, dizziness, headache, trouble breathing, dark urine, yellowing skin or eyes
  • High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
  • Kidney stones—blood in the urine, pain or trouble passing urine, pain in the lower back or sides
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

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