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Kaletra

Kaletra Side Effects

Ally Tsai, PharmDCydnee Ng, PharmD
Reviewed by Ally Tsai, PharmD, Cydnee Ng, PharmD
Last reviewed on September 13, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Adults:

  • Diarrhea (20%)
  • Respiratory tract infection (8-14%)
  • Nausea (10%)
  • Feeling weak (8%)
  • High cholesterol levels (7%)
  • Vomiting (7%)
  • Belly pain (6%)
  • Muscle, joint, or back pain (6%)
  • Headache or migraine (6%)

Children:

  • Changes in taste (21%)
  • Vomiting (21%)
  • Diarrhea (12%)

Less Common Side Effects

Adults:

  • Stomach flu
  • Indigestion
  • Acid reflux
  • Gassy
  • Constipation
  • Hemorrhoids
  • Nerve pain (tingling or prickling in arms or legs)
  • Dizziness
  • Anxiety
  • Night sweats
  • Trouble sleeping
  • Skin infection
  • Changes in weight
  • Changes in appetite
  • High blood pressure
  • Erectile dysfunction (in males)
  • Irregular periods (in females)

Kaletra serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reactions: facial swelling, hives, rash, itchy skin, blistering or peeling of skin, body aches, trouble breathing
  • Serious liver problems: nausea, vomiting, not feeling hungry, pain in the right side of the stomach, yellowing of the whites of the eyes or skin, dark-colored urine, light-colored stool
  • Abnormal heart rhythm: chest pounding, trouble breathing, chest pain, feeling faint or lightheaded

Source: DailyMed

The following Kaletra side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Bloating

blurred vision

chills

constipation

darkened urine

dry mouth

fast heartbeat

fever

flushed, dry skin

fruit-like breath odor

increased hunger

increased thirst

increased urination

indigestion

loss of appetite

loss of consciousness

nausea

pains in the stomach, side, or abdomen, possibly moving to the back

sweating

troubled breathing

unexplained weight loss

vomiting

yellow eyes or skin

Incidence not known

Blistering, peeling, or loosening of the skin

chest pain or discomfort

cough

diarrhea

itching

joint or muscle pain

lightheadedness, dizziness, or fainting

red skin lesions, often with a purple center

red, irritated eyes

slow or irregular heartbeat

sore throat

sores, ulcers, or white spots in the mouth or on the lips

unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Agitation

confusion

cool, sweaty skin

decreased appetite

decreased awareness or responsiveness

decreased urine output

depression

fast, irregular, or pounding heartbeat

fast, shallow breathing

general feeling of discomfort

headache

hostility

irritability

muscle pain or cramping

muscle twitching

pounding, slow heartbeat

rapid weight gain

seizures

severe sleepiness

stomach discomfort

swelling of the face, ankles, or hands

swelling of the feet or lower legs

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abnormal stools

belching

heartburn

lack or loss of strength

pain

skin rash

trouble with sleeping

Incidence not known

Redistribution of body fat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Ally Tsai, PharmD
Reviewed by:
Ally Tsai, PharmD
Ally Tsai, PharmD, is a medication therapy management (MTM) pharmacist with 6 years of experience. As an MTM pharmacist, she helps people with complex medication regimens get the best results by conducting comprehensive medication reviews.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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