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Mnexspike

Mnexspike Side Effects

Kristianne Hannemann, PharmDCydnee Ng, PharmD
Reviewed by Kristianne Hannemann, PharmD, Cydnee Ng, PharmD
Last reviewed on October 20, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Pain at the injection site
  • Feeling tired
  • Headache
  • Muscle pain
  • Joint pain
  • Chills
  • Nausea or vomiting
  • Swelling or tenderness of lymph nodes in the armpit of the injected arm

Less Common Side Effects

  • Fever
  • Redness or swelling at the injection site

Mnexspike serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Inflammation or swelling of the heart: chest pain, shortness of breath, a racing heart
  • Serious allergic reaction: trouble breathing; rash; hives; swelling of the face, lips, tongue, or throat
When do Mnexspike possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Pain at injection site
Feeling tired
Headache
Muscle or joint pain
Chills

Source: FDA

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The following Mnexspike side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Heart muscle inflammation—unusual weakness or fatigue, shortness of breath, chest pain, fast or irregular heartbeat, dizziness, swelling of the ankles, feet, or hands

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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