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Mifepristone Coupon - Mifepristone 300mg tablet

mifepristone

Generic Mifeprex
Used for Birth Control, Cushing's Syndrome

Mifepristone (Mifeprex) is used together with misoprostol (Cytotec) for medical abortion (using prescribed medications to end a pregnancy). These medications are typically used in people no more than 10 weeks pregnant. In some cases, it can be prescribed to people up to 11 weeks pregnant. Mifepristone (Mifeprex) is only available by prescription in certain U.S. states from certain healthcare providers (including some pharmacies). Taking mifepristone (Mifeprex) with misoprostol (Cytotec) can cause side effects like nausea and cramps. Vaginal bleeding is also an expected symptom after you've taken these abortion pills, but a lot of heavy bleeding can be a sign of serious complications. You'll need to follow up with your provider to make sure your pregnancy has ended completely.

Reviewed by:Last reviewed on July 26, 2023
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What is Mifepristone (Mifeprex)?

What is Mifepristone (Mifeprex) used for?

How Mifepristone (Mifeprex) works

Mifepristone (Mifeprex) is an antiprogestin medication. It blocks the effects of progesterone, a natural sex hormone that's important in starting and continuing a pregnancy. By blocking progesterone, mifepristone (Mifeprex) prevents a pregnancy from continuing.

Mifepristone (Mifeprex) is taken along with misoprostol (Cytotec). This additional medication causes your uterus to contract and push the pregnancy tissue out of your body. These two medications work together to end a pregnancy.

Drug facts

Common BrandsMifeprex
Drug ClassAntiprogestin
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Mifepristone (Mifeprex)

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (51-75%)
  • Weakness (55-58%)
  • Fever or chills (48%)
  • Vomiting (37-48%)
  • Headache (41-44%)
  • Diarrhea (18-43%)
  • Dizziness (39-41%)

Less Common Side Effects

  • Stomach pain or cramping
  • Vaginal or uterine bleeding
  • Anemia (low red blood cell count)
  • Fast heart rate
  • Lightheadedness
  • General pain

Mifepristone (Mifeprex) serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious infection: fever that doesn't go away (temperature of 100.4ºF or greater for more than 4 hours); severe stomach pain; stomach discomfort; weakness, nausea, vomiting, or diarrhea for more than 24 hours after taking misoprostol (Cytotec)
  • Heavy vaginal bleeding for a long time
  • Fainting

Source: DailyMed

The following Mifepristone (Mifeprex) side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Excessively heavy vaginal bleeding

unusual tiredness or weakness

Incidence not known

Chest pain or discomfort

confusion

cough or hoarseness

fast, weak pulse

fever or chills

lower back or side pain

pain or discomfort in the arms, jaw, back, or neck

painful or difficult urination

pale, cold, or clammy skin

shortness of breath

sudden increase in stomach or shoulder pain

sweating

unusual or large amount of vaginal bleeding

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abdominal or stomach pain or uterine cramping

back pain

diarrhea

dizziness

headache

nausea or vomiting

Less common

Acid or sour stomach

anxiety

belching

cough

fainting or lightheadedness when getting up from a lying or sitting position

fever

flu-like symptoms

headache

heartburn

increased clear or white vaginal discharge

indigestion

itching of the vagina or genital area

lack or loss of strength

pain during sexual intercourse

pain or tenderness around the eyes and cheekbones

pale skin

shaking chills

stomach discomfort, upset, or pain

stuffy or runny nose

tightness of the chest

trouble sleeping

troubled breathing

troubled breathing, exertional

unusual bleeding or bruising

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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$46736.64(Save 77.91%)
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Pros and cons of Mifepristone (Mifeprex)

Pros

  • No surgery required to end pregnancy
  • Between 93% and 98% effective at ending pregnancy through 10 weeks
  • Might be more affordable than a surgery to end pregnancy
  • Can safely take at home under the care of a certified healthcare provider

Cons

  • Requires close contact with your healthcare provider to make sure the medication worked
  • Commonly causes cramps, vaginal bleeding, and nausea
  • Risk of serious bleeding or infections
  • Can't take if you have an ectopic pregnancy
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Pharmacist tips for Mifepristone (Mifeprex)

pharmacist
  • Be sure to discuss with your healthcare provider about what to expect after you take mifepristone (Mifeprex). There can be some side effects such as cramping, nausea, and heavy bleeding.
  • You must follow up with your healthcare provider 1 to 2 weeks after you take mifepristone (Mifeprex). Your provider will need to examine you to make sure the medications worked and that there are no complications.
  • If you need to go to the emergency room or see a different provider for any reason during the process, make sure to let them know you're currently having a medical abortion.
  • Although mifepristone (Mifeprex) with misoprostol (Cytotec) works very well at ending a pregnancy, there's a small chance that it won't work. If this is the case, your healthcare provider will discuss with you about your options to complete the abortion. One possible option is through certain surgical procedures.
  • Let your healthcare provider know about all the medications you're taking, including over-the-counter (OTC) medications and supplements, so they can make sure mifepristone (Mifeprex) is safe for you to take. Certain medications, like carbamazepine (Tegretol), can affect how well mifepristone (Mifeprex) works. Other medications might raise your risk for side effects.
  • Let your healthcare provider know if you're currently breastfeeding when you're discussing plans for medical abortion. Mifepristone (Mifeprex) can pass into your breast milk, but we don't know the effects of this medication in breastfed babies. Mifepristone (Mifeprex) might not be the best option for you.
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Risks and warnings for Mifepristone (Mifeprex)

Mifepristone (Mifeprex) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Serious infection

Black Box WarningRarely, serious and sometimes life-threatening infections have happened after an abortion happens, including after taking mifepristone (Mifeprex). If you have a fever greater than 100.4ºF for more than 4 hours, severe stomach pain, or tenderness in the pelvic area during the days following your medical abortion, contact your healthcare provider or get emergency help right away. Also get medical attention right away if you experience stomach pain or discomfort, weakness, nausea, vomiting, or diarrhea for more than 24 hours after taking misoprostol (Cytotec). These all might be signs of a serious infection.

Serious vaginal bleeding

Black Box WarningVaginal bleeding is normal and expected during a medical abortion. But if it lasts for a long time and is extremely heavy (soaking through two thick, full-size sanitary pads per hour for two consecutive hours), then go to the emergency room right away. This can be a sign of an incomplete abortion, which needs to be immediately resolved to prevent shock.

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Mifepristone (Mifeprex) dosage

The average cost for 60 tablets of 300mg of Mifepristone (Mifeprex) is $10,325.11 with a free GoodRx coupon. This is 77.91% off the average retail price of $46,736.64.
tabletTablet
DosageQuantityPrice as low asPrice per unit
300mg60 tablets$10,325.11$172.09

Typical dosage for Mifepristone (Mifeprex)

This medication is used together with misoprostol (Cytotec). It must be taken as directed by your healthcare provider.

  • Day 1: Take one 200 mg tablet of mifepristone (Mifeprex) by mouth as a single dose.

  • Day 2 or 3 (between 24 and 48 hours after mifepristone (Mifeprex)): Take 800 mcg (four 200 mcg tablets) of misoprostol (Cytotec) by placing the tablets in your mouth alongside your cheeks and letting them dissolve. Place two tablets between the cheek and gum on the left side of your mouth. Place the other two tablets on the right side of your mouth in a similar way as the first two. Allow them to dissolve against your cheek over 30 minutes. Then, swallow any remaining tablet bits with water or other liquid.

Note:

  • Discuss with your provider about your medical abortion plan and dosing, since it might differ depending on your situation.
  • You must follow up with your healthcare provider 1 to 2 weeks after taking mifepristone (Mifeprex) to make sure the pregnancy has ended completely.
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Interactions between Mifepristone (Mifeprex) and other drugs

Mifepristone (Mifeprex) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Mifepristone (Mifeprex). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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How much does Mifepristone (Mifeprex) cost?

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Mifepristone (Mifeprex) (generic)
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$10,325.11

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Mifepristone (Mifeprex) contraindications

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Mifepristone (Mifeprex) will not be safe for you to take.

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News about Mifepristone (Mifeprex)

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Mifepristone (Mifeprex) images

Yellow And Brown Oval A33 - Mifepristone 300mg Tablet
This medicine is Yellow And Brown, Oval Tablet Imprinted With "A33".Yellow And Brown Oval A33 - Mifepristone 300mg Tablet
Yellow Oval Corcept And 300 - Mifepristone 300mg Tablet
This medicine is Yellow, Oval Tablet Imprinted With "300" And "Corcept".Yellow Oval Corcept And 300 - Mifepristone 300mg Tablet

References

Best studies we found

American College of Obstetricians and Gynecologists. (2023). What is the difference between abortion pills and morning-after pills?

American College of Obstetricians and Gynecologists. (2023). What to know about abortion and miscarriages with or without mifepristone.

Anderson, K. E. (2022). Porphyrias. National Organization for Rare Disorders.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.