The average cost for 24 tablets of 2.5mg of Methotrexate is $13.46 with a free GoodRx coupon. This is 53.20% off the average retail price of $28.76.
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TabletDosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
2.5mg | 24 tablets | $13.46 | $0.56 |
VialDosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
2ml of 25mg/ml | 2 vials | $12.10 | $6.05 |
10ml of 25mg/ml | 1 vial | $17.69 | $17.69 |
1g | 12 vials | $235.21 | $19.60 |
4ml of 25mg/ml | 1 vial | $17.23 | $17.23 |
Typical dosage for Methotrexate
Depending on your condition, Methotrexate is given as an injection into the vein (intravenously, IV); into the fluid around the spinal cord (intrathecally), into the muscle (intramuscularly, IM); or under the skin (subcutaneously, SC).
The dose of Methotrexate can vary since it depends on what condition you’re taking the medication for. Sometimes, the dose depends on your body size or body surface area (BSA) in m2 units.
The manufacturer dosages for certain conditions are listed below as examples. But your dose and how often you need injections might be different depending on the specific dosing protocol that your provider uses. Your provider might adjust the dose to best fit your needs.
Cancer
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Acute lymphoblastic leukemia: The typical dose ranges from 10 mg/m2 to 5,000 mg/m2 IV. Lower doses (up to 30 mg/m2 per week) can be given IM.
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Meningeal leukemia: The dose depends on age and ranges from 6 mg to 15 mg injected intrathecally. For treatment, Methotrexate is given anywhere from every other day to twice weekly. For prevention, the medication is given once weekly.
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Osteosarcoma: The typical dose is 12 grams/m2 IV. It’s given with other chemotherapy.
Non-cancer conditions
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Rheumatoid arthritis: The typical starting dose is 7.5 mg IM once weekly.
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Polyarticular juvenile idiopathic arthritis: The typical starting dose is 10 mg/m2 IM or SC once weekly.
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Psoriasis: The typical dose is 10 mg to 25 mg IM or IV once weekly.
