Verapamil is a non-dihydropyridine calcium channel blocker. It's used to treat high blood pressure, arrhythmias, and chest pain (or angina) in adults. Verapamil works by slowing your heart rate and relaxing your blood vessels. This medication is taken by mouth typically about 3 to 4 times per day. Side effects can include constipation, dizziness, and nausea.
Verapamil is a non-dihydropyridine calcium channel blocker. It lowers blood pressure and helps with irregular heart rhythm (arrhythmia) by slowing your heart rate and relaxing your blood vessels. This also helps your heart to get more oxygen so it doesn't need to work as hard to pump, which can help with chest pain.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Blue lips and fingernails
blurred vision
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
confusion
coughing that sometimes produces a pink frothy sputum
difficult, fast, noisy breathing, sometimes with wheezing
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
increased sweating
lightheadedness, dizziness, or fainting
pale skin
shortness of breath
slow or irregular heartbeat
sweating
swelling in legs and ankles
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Difficulty having a bowel movement (stool)
headache
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
It depends on what you're using verapamil for. For example, the maximum effects of verapamil for an irregular heart beat can be seen within 2 days. But for high blood pressure, you probably won't experience the full effect of the medication until 2 to 4 weeks later. To keep track of how well verapamil is working, measure your blood pressure regularly at home or make a log of when you experience symptoms like chest pain or tightness. You're recommended to share the log with your provider at your appointments so they can better care for your health.
No, verapamil isn't a beta blocker; it's a calcium channel blocker. Both medication classes work on the heart and blood vessels to treat high blood pressure or chest pain, but they work in different ways. In general, providers won't prescribe verapamil with beta blockers because of the higher risk of heart-related side effects.
It can take a little more than a day for most of verapamil to leave your body after a single dose. But it can take up to 3 days as you continue taking the medication. This time frame is estimated based on the half-life of verapamil. It can differ from person to person depending on other factors, such as your age, how long you've been taking verapamil, and if you have liver problems.
Yes, verapamil can lower heart rate. This is how verapamil works to treat certain types of irregular heart beats (arrhythmias).
Yes, verapamil can potentially cause constipation. If you become constipated, try eating foods high in fiber and drinking more fluids. Ask your provider whether it's safe for you to take any over-the-counter stool softeners or laxatives. If your constipation doesn't improve, let your provider know.
No, verapamil doesn't typically cause weight gain due to a larger appetite. But, calcium channel blockers like verapamil can cause fluid to build up in your body to the point where you might feel or notice changes in weight. Let your provider know if you notice any swelling in your arms or legs, especially if it isn't going away or getting better. They might ask you to come into the clinic for a check up because swelling can symptom of heart failure, a rare side effect of verapamil.
There are several medications that interact with verapamil. Depending on what you're taking, your provider might consider prescribing safer alternatives, or adjust the doses of some medications to prevent severe side effects. For example, if you're taking simvastatin (Zocor) or digoxin (Lanoxin) with verapamil, your provider will need to lower the doses of those medication to prevent side effects. You're also recommended to avoid alcohol while taking verapamil because verapamil can raise your blood alcohol levels and worsen the effects of alcohol. It's very important to tell your provider and pharmacist about all of the medications you're taking before and during treatment with verapamil to make sure your treatment is as safe for you as possible.
Verapamil can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Verapamil can worsen heart failure, especially in people who already have heart problems that affect how well blood is pumped to the rest of the body. Let your provider know if you experience symptoms of heart failure, such as chest pain, difficulty breathing, dizziness, tiredness, swollen legs and feet, or bloating.
Verapamil can cause your blood pressure to drop too much, which can make you feel dizzy, tired, or lightheaded. This is a common side effect of blood pressure medications, especially when starting the medication and when the dose is raised. If your blood pressure drops too much and you feel too dizzy, make sure to sit down slowly while holding onto something. Let your provider know because they might need to adjust the dose of your medication. If you fall and hit your head, get medical help right away.
Although rare, verapamil can cause or worsen heart block, which is when your heart rate is slowed down. This can cause you to feel weak or lightheaded and might even cause you to pass out. You're at higher risk if you're taking other medications that lower your heart rate, such as digoxin (Lanoxin) or a beta-blocker (e.g., propranolol (Inderal)), or if you have other medical conditions that slow your heart rate or affect your heart rhythm. Make sure your provider knows your entire medical history before starting verapamil. Ask your provider if you're not sure whether this medication is safe for you.
Although rare, verapamil can raise your liver enzymes, which can lead to liver problems if not properly treated. This typically occurred within 1 to 8 weeks of starting verapamil. Your provider might check your liver tests before you start this medication and regularly afterwards to make sure it doesn't become a serious problem. If you notice severe nausea, vomiting, right-sided stomach pain, fatigue, low or no appetite, or yellowing of the skin or eyes, get medical help right away.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 80mg | 90 tablets | $14.75 | $0.16 |
| 120mg | 90 tablets | $18.41 | $0.20 |
| 40mg | 90 tablets | $11.46 | $0.13 |
Your provider might adjust your dose based on things like how well you're responding to the medication, your age, your height, if you have liver problems, and if you're having side effects.
There's also an injectable form of verapamil that's given into the veins (IV) for people in the hospital.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Verapamil will not be safe for you to take.