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Verapamil Dosages: Your GoodRx Guide

Daphne Berryhill, RPhAustin Ulrich, PharmD, BCACP
Published on March 22, 2023

Key takeaways:

  • Verapamil is a type of calcium channel blocker (CCB). It’s used to treat high blood pressure and other heart conditions. Its oral forms include immediate-release (IR) tablets and extended-release (ER) tablets and capsules.

  • Your verapamil dosage can vary based on why you’re taking it, which form you’re taking, and other personal factors.

  • Verapamil IR is usually taken three to four times a day. Verapamil ER tablets and capsules are usually only taken once a day.

  • Verapamil IR and ER are available as lower-cost generics. GoodRx can help you save over 60% off the average retail price at certain pharmacies.

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Verapamil is in a class of medications called calcium channel blockers (CCBs). It’s FDA approved to treat many heart-related conditions, including chest pain, irregular heartbeats, and high blood pressure.

In this guide, we’ll go over typical verapamil dosages. But your healthcare provider may prescribe a different dosage from what’s discussed here — one that’s personalized for you. Make sure to follow their instructions closely and discuss any questions you have with them.

What dosage forms of verapamil are available?

Verapamil comes in immediate-release (IR) and extended-release (ER) forms. They’re all available as lower-cost generic options. The ER forms also come in brand-name versions.

  • IR forms: tablet and injection

  • ER forms: tablet (Calan SR) and capsule (Verelan, Verelan PM)

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If you’re prescribed the IR tablets, you’ll take them more frequently than the ER products. This is because the IR tablets don’t last as long in the body. The different oral verapamil forms and their FDA-approved uses are below:

Dosage forms

Brand-name examples

FDA-approved uses

Verapamil IR tablets



N/A

High blood pressure

Chest pain

Irregular heartbeat

Verapamil ER tablets

Calan SR

High blood pressure

Verapamil ER capsules 

Verelan

Verelan PM

High blood pressure

What’s the typical verapamil dosage for adults?

The typical verapamil dosage depends on many factors. But regardless of why you take verapamil, you’ll likely start at a lower dose. Your healthcare provider may slowly raise your dose over the following days to weeks depending on how your body responds.

Your daily dose will usually stay the same if you switch from an IR to ER product. But switching from one ER product to another may not be as straightforward. Check with your provider before switching products.

High blood pressure

When verapamil is used for high blood pressure (hypertension), it’s commonly used in combination with another medication. This may include angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs).

The usual doses of verapamil IR and ER are discussed in the table below.

Medication name

Usual starting dose

Maximum dose

Verapamil IR tablets

80 mg three times a day

120 mg three times a day

Verapamil ER tablets

180 mg once in the morning

240 mg twice daily

Verapamil ER capsules

Verelan: 240mg once in the morning

Verelan PM: 200 mg at bedtime

Verelan: 480mg once in the morning

Verelan PM: 400 mg at bedtime

Chest pain

Verapamil IR is approved to treat chest pain (angina). The usual verapamil dosage for angina is 80 mg to 120 mg three times a day.

Atrial fibrillation or atrial flutter

Verapamil is also used for conditions that are caused by irregular heartbeats (arrhythmias). These include atrial fibrillation and atrial flutter.

The usual daily dose of verapamil IR is 240 mg to 320 mg (divided into 3 or 4 doses) for “rate control.” Rate control medications slow down the heart rate.

Verapamil ER isn’t FDA approved for arrhythmias, but the national guidelines from the American College of Cardiology (ACC) and American Heart Association (AHA) recommend verapamil ER for atrial fibrillation at a dose of 180 mg to 480 mg once daily.

Paroxysmal supraventricular tachycardia

Paroxysmal supraventricular tachycardia (PSVT) is another type of arrhythmia. The manufacturer-recommended daily dose of verapamil IR is 240 mg to 480 mg (divided into 3 or 4 doses).

The ACC/AHA guidelines recommend a lower starting dose of 120 mg per day and a maximum dose of 480 mg per day. Though verapamil ER isn’t FDA approved for PSVT, the guidelines state that verapamil IR or ER can be used for PSVT.

Are there any necessary dosage adjustments?

Your healthcare provider might make dosage adjustments when prescribing verapamil depending on individual factors. For example, in older adults or people with a lower body weight, verapamil levels can build up in the body. So your healthcare provider might start you on a lower dose initially. You may also need a lower dose of verapamil if you have any of the following conditions:

Verapamil also has many drug interactions. This can result in lower or higher levels of verapamil or the interacting medication. So you might need dosage adjustments depending on what medications you take. This includes other blood pressure medications. Before starting verapamil, give your healthcare provider a list of all the medications and supplements you take. This will help them check for interactions.

Are there any specific instructions for taking verapamil?

The IR and ER verapamil tablets can be cut in half and each piece swallowed whole.

The ER capsules should be swallowed whole. If you have trouble swallowing pills, you can also open the capsules and mix the contents with one tablespoon of applesauce. Just make sure you swallow the mixture without chewing and drink a glass of cold water afterwards.

The ER tablets should be taken with food. Other forms of verapamil can be taken with or without food.

What happens if you miss a dose of verapamil?

If you miss a dose of verapamil, take it as soon as you remember. But if it’s close to your next scheduled dose, skip the missed dose and take your next dose at your usual time. Don’t try to make up for a missed dose by taking two doses together.

Tell your healthcare provider if you've missed several doses of verapamil. They may want you to check your blood pressure. Or they may adjust your dosing schedule. If you have trouble remembering to take your medications, you may want to consider setting reminders on your smartphone or getting a medication reminder app to help you remember.

What should you do if you take too much verapamil?

Taking too much verapamil can lead to low blood pressure and make other side effects more likely. This includes constipation, dizziness, and headaches. More seriously, this can include a slow heart rate or very low blood pressure.

If you take too much verapamil, you may need close monitoring for at least 48 hours. So even if you’re not sure how much verapamil you took, talk with your healthcare provider right away if you think you took too much. If you’re experiencing symptoms, call 911 or Poison Control at 1-800-222-1222.

How to save on verapamil

There are many ways to save on verapamil IR and ER. Both are available as lower-cost generics.

GoodRx may be able to help you save over 60% off the average retail price of the generic versions of verapamil IR and ER. With a free GoodRx discount, certain pharmacies may carry verapamil products for as low as:

The bottom line

Your verapamil dosage depends on which product you're taking, what you’re taking it for, and other individual factors. Verapamil IR tablets are usually taken multiple times a day. Verapamil ER tablets and capsules are typically only taken once a day.

Your healthcare provider will generally start you on a lower dose of verapamil and slowly increase it depending on how you respond. Share your full medical history and updated medication list with your provider. This will help them prescribe a dose that’s best for you.

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Why trust our experts?

Daphne Berryhill, RPh
Daphne Berryhill, RPh, has two decades of experience as a clinical pharmacist. She spent most of her career in the Chicago area practicing in-home infusion.
Amy B. Gragnolati, PharmD, BCPS
Amy Gragnolati, PharmD, BCPS, is a pharmacy editor for GoodRx. Amy currently holds her pharmacist license in Georgia and California.
Austin Ulrich, PharmD, BCACP
Austin Ulrich, PharmD, BCACP, is a board-certified ambulatory care clinical pharmacist. In his early career, he provided direct patient care in a variety of settings, including hospital and community pharmacies, and in a primary care clinic as a clinical pharmacist.

References

American College of Cardiology. (n.d.). Verapil (cancal, verelan, calan SR, isoptin) considerations for use

American Heart Association. (2022). Prinzmetal’s or prinzmetal angina, variant angina and angina inversa

View All References (12)

Amsterdam, E. A., et al. (2014). 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: Executive summary. Circulation

Bryant Ranch Prepack. (2022). Verapamil hydrochloride [package insert]

Denton Pharma Inc. (2023). Verapamil hydrochloride [package insert]

Fihn, S. D., et al. (2012). 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Journal of the American College of Cardiology

January, C. T., et al. (2014). 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation. Circulation

Lannett Company Inc. (2022). Verelan [package insert]

Lannett Company Inc. (2022). Verelan PM [package insert]

MedlinePlus. (2017). Verapamil

Page, R. L., et al. (2015). 2015 ACC/AHA/HRS guideline for the management of adult patients with supraventricular tachycardia. Circulation

Robbins, M. S., et al. (2016). Treatment of cluster headache: The American Headache Society evidence-based guidelines. Headache: The Journal of Head and Face Pain

Rodriguez, Z. M., et al. (2022). Atrial flutter. StatPearls

Wang, A. L., et al. (2017). New generations of dihydropyridines for treatment of hypertension. Journal of Geriatric Cardiology: JGC.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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