Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Xyrem vs. Lumryz

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Sodium oxybate (Xyrem)
    Lumryz (sodium oxybate)
  • Sodium oxybate (Xyrem)
    Lumryz (sodium oxybate)

  • Summary of Xyrem vs. Lumryz

    Summary for CNS depressant
    Prescription only

    Sodium oxybate (Xyrem) is for people 7 years and older with narcolepsy. It's used to treat cataplexy (sudden muscle weakness after strong emotions) and excessive daytime sleepiness (EDS). This medication works as a central nervous system depressant. It's a liquid solution that you have to mix with water before you take it. The dosage is taken by mouth two times at night, once at bedtime, and then again 2.5 to 4 hours later. Side effects include nausea and dizziness. Some people, but especially children, might wet the bed. Sodium oxybate (Xyrem) is available with a prescription as a brand-name and generic medication.

    Summary for CNS depressant
    Prescription only

    Lumryz (sodium oxybate) is used to help adults and children 7 years and older with narcolepsy. It treats cataplexy and excessive daytime sleepiness. This medication works as a central nervous system depressant. Lumryz (sodium oxybate) comes as packets of powder that you need to mix with water before you take your dose. It's an extended-release medication that you only need to take just once each night. Side effects can include nausea, dizziness, headache, and bedwetting. Lumryz (sodium oxybate) is only available by prescription as a brand-name medication.

  • Indications of Xyrem vs. Lumryz

    Indications for
    •Excessive daytime sleepiness (EDS) or cataplexy in people with narcolepsy
    Indications for
    •Excessive daytime sleepiness (EDS) or cataplexy in people with narcolepsy

  • Pros and Cons of Xyrem vs. Lumryz

    Pros and Const for CNS depressant
    Pros
    •A first-choice medication for narcolepsy
    •Okay for children 7 years and older with narcolepsy to take
    •Is a liquid mixture, so no need to swallow whole pills
    •Dose can be adjusted if needed
    Cons
    •Need to take two doses each night (one at bedtime, and another in the middle of the night)
    •Need to mix the medication with water before taking
    •Is a controlled substance, so there are special requirements to getting the medication filled
    •Can't take with sedatives
    Pros and Const for CNS depressant
    Pros
    •Taken just once at bedtime each night (no need to wake up in the middle of the night for a second dose)
    •Can okay for children 7 years and older with narcolepsy to take
    •Becomes a liquid once mixed, so you don't need to swallow a pill
    Cons
    •Need to mix the medication with water before taking
    •Is a controlled substance, so there are special requirements to getting the medication filled
    •Might not be the best option for people with liver problems

  • Common Side Effects of Xyrem vs. Lumryz

    Common Side Effects for

    Adults:

    •Nausea (up to 20%)
    •Dizziness (up to 15%)
    •Vomiting (up to 11%)
    •Sleepiness (up to 8%)
    •Bedwetting (up to 7%)
    •Tremor or shakiness (up to 5%)

    Children:

    •Nausea (20%)
    •Bedwetting (19%)
    •Vomiting (18%)
    •Headache (17%)
    •Weight loss (13%)
    •Poor appetite (9%)
    •Dizziness (8%)
    •Sleepwalking (6%)
    Common Side Effects for
    •Bedwetting (up to 9%)
    •Nausea (up to 8%)
    •Headache (up to 7%)
    •Dizziness (up to 6%)
    •Vomiting (up to 6%)

  • Warnings of Xyrem vs. Lumryz

    Common Side Effects for
    •Potential for misuse
    •Changes in mental alertness
    •Dangerously slowed breathing
    •Only available through the Xyrem REMS program
    •Behavior changes, including depression and suicidal thoughts
    •Unusual sleep behaviors (e.g., sleepwalking)
    •Contains a high amount of sodium
    Common Side Effects for
    •Potential for misuse
    •Changes in mental alertness
    •Dangerously slowed breathing
    •Only available through the Lumyrz REMS program
    •Behavior changes, including depression and suicidal thoughts
    •Unusual sleep behaviors (e.g., sleepwalking)
    •Contains a high amount of sodium

  • Prices with our coupons for Xyrem vs. Lumryz

    Learn more about Sodium oxybate
    Learn more about Lumryz

Compare other Narcolepsy drugs

Wakix vs XyremXywav vs XyremAdderall vs ConcertaAdderall vs StratteraAdderall vs XanaxAdderall Xr vs AdderallArmodafinil vs AdderallAtivan vs AdderallAzstarys vs AdderallDaytrana vs AdderallDesoxyn vs AdderallDexedrine vs AdderallDextroamphetamine vs AdderallEvekeo vs AdderallFocalin vs AdderallGuanfacine vs AdderallIntuniv vs AdderallKapvay vs AdderallLexapro vs AdderallModafinil vs AdderallMydayis vs AdderallNamenda vs AdderallPhentermine vs AdderallProzac vs AdderallQelbree vs AdderallRitalin vs AdderallWakix vs AdderallWakix vs NuvigilWakix vs SunosiXywav vs Sunosi
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.