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Vimpat vs. Motpoly XR

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Lacosamide

(Vimpat)

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Motpoly XR

(lacosamide)

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Summary for Vimpat

Prescription only

Lacosamide (Vimpat) is an antiepileptic. People 1 month and older can take it on its own or with other antiepileptics for partial-onset seizures (also called focal aware seizures). It's also an add-on medication for people 4 years and older who have primary generalized tonic-clonic (PGTC) seizures (or grand mal seizures). Lacosamide (Vimpat) comes as tablets and an oral solution that's taken by mouth twice a day. It's also available as an injection that's used in the hospital. Side effects include dizziness, headache, and nausea. Lacosamide (Vimpat) comes as both brand-name and generic versions, but it's a controlled substance.

Indications for Vimpat

Pros and Cons for Vimpat

Pros

  • Can take with other seizure medications
  • Available as a tablet and oral solution
  • Okay for children 1 month of age and older with partial-onset seizures and children 4 years and older with PGTC seizures

Cons

Common Side Effects for Vimpat

  • Dizziness (31%)
  • Headache (13%)
  • Nausea (11%)
  • Double vision (11%)
  • Vomiting (9%)
  • Tiredness (9%)
  • Blurred vision (8%)
  • Problems with movement or coordination (8%)
  • Sleepiness (7%)
  • Tremor (7%)

Warnings for Vimpat

  • Risk of suicidal thoughts and behavior
  • Dizziness and problems with controlling movements
  • Abnormal heartbeat
  • Withdrawal seizures
  • Allergic reactions
  • Caution use in people with phenylketonuria (PKU) - oral solution only

Summary for Motpoly XR

Prescription only

Motpoly XR is the brand name for the extended-release lacosamide capsules. It's an antiepileptic medication. It can treat partial-onset seizures (also called focal aware seizures) and primary generalized tonic-clonic (PGTC) seizures. This medication is approved for adults and children who weigh at least 110 lbs. The capsules are swallowed whole once a day. In general, your dose is adjusted based on how well the medication works for you. Some common side effects include dizziness, headaches, and nausea.

Indications for Motpoly XR

Pros and Cons for Motpoly XR

Pros

Cons

  • Is a controlled substance, so it has special requirements to get the prescription filled
  • Must swallow the capsule whole, so might not be a good option for people with trouble swallowing
  • Not approved for children weighing less than 110 lbs

Common Side Effects for Motpoly XR

  • Dizziness
  • Headache
  • Nausea
  • Vomiting
  • Double vision
  • Blurred vision
  • Sleepiness
  • Fatigue or tiredness
  • Having problems with movement or coordination

Warnings for Motpoly XR

  • Risk of suicidal thoughts and behavior
  • Dizziness and problems with coordination
  • Abnormal heart rhythm
  • Allergic reactions
  • Withdrawal seizures after stopping Motpoly XR (lacosamide) suddenly

Prices with our coupons for Vimpat vs. Motpoly XR

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Vimpat60 tablets / 200mg
$1,186.07$1,499.90
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Motpoly XR60 capsules / 200mg
$1,143.46$1,595.48
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