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Timolol vs. Combigan

Timolol is an eye drop medication that's used to lower pressure within the eye and treat glaucoma. This medication belongs to the drug class called beta blockers. Timolol can be used by itself or together with other eye drops. The usual dosage is a drop of timolol into the eye(s) once or twice a day. Common side effects include burning or stinging after you put in the eye drops, but this is generally a temporary feeling. Although the brand name Timoptic was discontinued, the generic version is still available.

• High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)

• Temporary burning or stinging in the eye after using

• Higher risk for heart failure
• Not recommended for people with breathing problems
• Hidden symptoms of low blood sugar
• Hidden symptoms of overactive thyroid
• Worsening of myasthenia gravis

Combigan is a combination eye drop containing brimonidine (an alpha agonist) and timolol (a beta blocker). It's used to lower high pressure inside the eye in adults with conditions like glaucoma or ocular hypertension. Typically, you apply one drop to the affected eye(s) twice daily, about 12 hours apart. Common side effects include eye redness, itching, or dryness. Combigan (brimonidine / timolol) is available as both a brand-name and generic medication.

Treatment of high pressure in the eye in people ages 2 years and older with:

• Ocular hypertension
• Open-angle glaucoma

Reported in up to 15% of people in clinical studies:

• Eye redness
• Eye itching
• Eye burning or stinging

• Only use in the eye
• Allergic reaction of the eye
• Interaction with inhaled beta agonists for asthma or COPD
• Worsening heart problems
• Worsening of other medical conditions
• Masked symptoms of low blood sugar in people with diabetes
• Masked symptoms of high thyroid hormone levels (hyperthyroidism)