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Tegretol vs. Vimpat

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Carbamazepine (Tegretol) and Vimpat (lacosamide) are both antiepileptic medications used to treat seizures, but they have some key differences. Carbamazepine is used for various types of seizures, trigeminal neuralgia, and bipolar I disorder (Equetro brand only), while Vimpat is used for partial-onset seizures and as an add-on for primary generalized tonic-clonic seizures. Carbamazepine is available in many forms, including pills, chewable tablets, and liquid, and is not a controlled substance. In contrast, Vimpat is a Schedule V controlled substance, meaning it has a potential for misuse and dependence. Carbamazepine works by blocking sodium channels in the brain, whereas Vimpat's exact mechanism is unclear but is thought to slow sodium channel activity. Common side effects of carbamazepine include dizziness, sleepiness, and stomach upset, while Vimpat can cause dizziness, headache, and nausea. Additionally, carbamazepine can interfere with hormonal birth control and requires routine blood tests, whereas Vimpat does not have these specific concerns.

Carbamazepine

(Tegretol)

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Lacosamide

(Vimpat)

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Summary for Tegretol

Prescription only

Carbamazepine (Tegretol) is an antiseizure medication used to treat different kinds of seizures. It can also help with trigeminal neuralgia, a type of facial nerve pain. Brand name Equetro is the only formulation that's approved to treat bipolar I disorder. Carbamazepine (Tegretol) available as pills and a liquid. Depending on formulation you take and what medical condition you have, carbamazepine (Tegretol) is taken by mouth 1 to 4 times per day. Common side effects include sleepiness, dizziness, and stomach upset.

Indications for Tegretol

Pros and Cons for Tegretol

Pros

  • Works well for different types of seizures and trigeminal neuralgia (facial nerve pain)
  • Helps stabilize mood in people with bipolar disorder (Equetro brand only)
  • Available as a lower-cost generic
  • Comes in many dosage forms (e.g., chewable tablets, oral pills, liquid form) for people who have difficulty swallowing pills

Cons

  • Might need to take the immediate-release form of the medication up to 4 times a day
  • Can cause a lot of side effects
  • Might require routine blood testing while taking the medication to see how it's affecting your body
  • Can make hormonal birth control not work as well

Common Side Effects for Tegretol

  • Dizziness (44%)
  • Sleepiness (32%)
  • Nausea (29%)
  • Vomiting (18%)
  • Difficulty walking or keeping balance (15%)
  • Constipation (10%)
  • Itching (8%)
  • Dry mouth (8%)
  • Weakness (8%)
  • Rash (7%)
  • Blurry vision (6%)
  • Speech problems (6%)

Warnings for Tegretol

  • Severe skin reactions
  • Low blood cell counts
  • Severe allergic reactions
  • Suicidal thoughts or behavior
  • Harm to unborn babies
  • Withdrawal
  • Difficulty with speech, concentration, and movement
  • Liver problems
  • Low sodium levels
  • High eye pressure
  • Heart block (heart rhythm problems)

Summary for Vimpat

Prescription only

Lacosamide (Vimpat) is an antiepileptic. People 1 month and older can take it on its own or with other antiepileptics for partial-onset seizures (also called focal aware seizures). It's also an add-on medication for people 4 years and older who have primary generalized tonic-clonic (PGTC) seizures (or grand mal seizures). Lacosamide (Vimpat) comes as tablets and an oral solution that's taken by mouth twice a day. It's also available as an injection that's used in the hospital. Side effects include dizziness, headache, and nausea. Lacosamide (Vimpat) comes as both brand-name and generic versions, but it's a controlled substance.

Indications for Vimpat

Pros and Cons for Vimpat

Pros

  • Can take with other seizure medications
  • Available as a tablet and oral solution
  • Okay for children 1 month of age and older with partial-onset seizures and children 4 years and older with PGTC seizures

Cons

Common Side Effects for Vimpat

  • Dizziness (31%)
  • Headache (13%)
  • Nausea (11%)
  • Double vision (11%)
  • Vomiting (9%)
  • Tiredness (9%)
  • Blurred vision (8%)
  • Problems with movement or coordination (8%)
  • Sleepiness (7%)
  • Tremor (7%)

Warnings for Vimpat

  • Risk of suicidal thoughts and behavior
  • Dizziness and problems with controlling movements
  • Abnormal heartbeat
  • Withdrawal seizures
  • Allergic reactions
  • Caution use in people with phenylketonuria (PKU) - oral solution only

Prices with our coupons for Tegretol vs. Vimpat

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Carbamazepine180 tablets / 200mg
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Vimpat60 tablets / 200mg
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