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Tegretol vs. Neurontin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Carbamazepine (Tegretol, Equetro) and gabapentin (Neurontin) are both antiepileptic medications, but they have different uses and mechanisms. Carbamazepine is used to treat various types of seizures, trigeminal neuralgia (a type of facial nerve pain), and bipolar I disorder (Equetro brand only). It works by blocking sodium channels in the brain. Gabapentin, on the other hand, is used for nerve pain from shingles and as an add-on treatment for partial seizures. It has a structure similar to gamma-aminobutyric acid (GABA), a calming brain chemical, but its exact mechanism is not fully understood. Carbamazepine is available in many forms, including pills, chewable tablets, and liquid, while gabapentin is available as tablets, capsules, and liquid. Both medications can cause dizziness and sleepiness, but carbamazepine has a broader range of side effects, including potential liver problems and low blood cell counts. Gabapentin is sometimes controlled in certain states due to its potential for misuse, unlike carbamazepine.

Carbamazepine

(Tegretol)

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Gabapentin

(Neurontin)

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Summary for Tegretol

Prescription only

Carbamazepine (Tegretol) is an antiseizure medication used to treat different kinds of seizures. It can also help with trigeminal neuralgia, a type of facial nerve pain. Brand name Equetro is the only formulation that's approved to treat bipolar I disorder. Carbamazepine (Tegretol) available as pills and a liquid. Depending on formulation you take and what medical condition you have, carbamazepine (Tegretol) is taken by mouth 1 to 4 times per day. Common side effects include sleepiness, dizziness, and stomach upset.

Indications for Tegretol

Pros and Cons for Tegretol

Pros

  • Works well for different types of seizures and trigeminal neuralgia (facial nerve pain)
  • Helps stabilize mood in people with bipolar disorder (Equetro brand only)
  • Available as a lower-cost generic
  • Comes in many dosage forms (e.g., chewable tablets, oral pills, liquid form) for people who have difficulty swallowing pills

Cons

  • Might need to take the immediate-release form of the medication up to 4 times a day
  • Can cause a lot of side effects
  • Might require routine blood testing while taking the medication to see how it's affecting your body
  • Can make hormonal birth control not work as well

Common Side Effects for Tegretol

  • Dizziness (44%)
  • Sleepiness (32%)
  • Nausea (29%)
  • Vomiting (18%)
  • Difficulty walking or keeping balance (15%)
  • Constipation (10%)
  • Itching (8%)
  • Dry mouth (8%)
  • Weakness (8%)
  • Rash (7%)
  • Blurry vision (6%)
  • Speech problems (6%)

Warnings for Tegretol

  • Severe skin reactions
  • Low blood cell counts
  • Severe allergic reactions
  • Suicidal thoughts or behavior
  • Harm to unborn babies
  • Withdrawal
  • Difficulty with speech, concentration, and movement
  • Liver problems
  • Low sodium levels
  • High eye pressure
  • Heart block (heart rhythm problems)

Summary for Neurontin

Prescription only

Gabapentin, also known by its brand name Neurontin, is used to treat nerve pain from shingles in adults. This medication can also help treat partial (focal) seizures in adults and children. Gabapentin (Neurontin) comes as pills and a liquid that you take by mouth. The dosage depends on things like what you're treating, how old you are, and how well the medication is working. In general, you take it 3 times a day. Common side effects include making you feel dizzy and sleepy.

Indications for Neurontin

Pros and Cons for Neurontin

Pros

  • An option for relieving nerve pain caused by shingles
  • Can take with other anti-seizure medications for partial-onset seizures in people 3 years and older
  • Available as a tablet, capsule, and liquid for those who have trouble swallowing pills

Cons

  • Usually need to taken three times per day
  • Can cause dizziness and sleepiness
  • Can cause withdrawal symptoms if you stop taking the medication too suddenly or too fast

Common Side Effects for Neurontin

  • Sleepiness (19%)
  • Dizziness (17%)
  • Poor muscle control or clumsiness (13%)
  • Fatigue (11%)

Warnings for Neurontin

  • Severe allergic reactions
  • Sleepiness, dizziness, and trouble concentrating
  • Risk of suicidal thoughts and behavior
  • Higher risk of seizures and other side effects if you stop the medication too suddenly or too fast
  • Dangerously slowed breathing
  • Changes in behavior in children

Prices with our coupons for Tegretol vs. Neurontin

Price Card Drug Icon
Carbamazepine180 tablets / 200mg
$38.31$154.29
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Gabapentin60 capsules / 300mg
$10.29$111.23
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