Key takeaways
Cromolyn (NasalCrom) and fluticasone (Flonase) are both nasal sprays used to treat allergy symptoms like a runny or itchy nose. However, they belong to different medication classes. Cromolyn is a mast cell stabilizer, while fluticasone is a corticosteroid. Cromolyn is available over-the-counter and is typically used 3 to 4 times a day, whereas fluticasone can be used once daily and is available both over-the-counter and by prescription. Cromolyn is safe for children as young as 2 years old, while fluticasone is generally recommended for children 4 years and older, though some formulations like Flonase Sensimist can be used in children as young as 2. Common side effects of cromolyn include brief stinging in the nose and nosebleeds, while fluticasone can cause headaches, sore throat, and nosebleeds. Fluticasone may also slow growth in children if used for more than 2 months a year and can increase the risk of eye problems and infections. Cromolyn does not cause rebound congestion, a risk associated with some nasal sprays, and is considered safe for people with high blood pressure.
