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Lovenox vs. Xarelto

Enoxaparin (Lovenox) is a blood thinner that's used to treat and prevent blood clots and other clotting-related conditions. It's given as an injection under the skin in the stomach. The dosing for enoxaparin (Lovenox) depends mostly on your weight, but also on why you need the medication. Enoxaparin (Lovenox) is a preferred choice for pregnant women, but it might not be the best option if they have prosthetic (artificial) heart valves. Side effects aren't common, but can include bleeding or bruising at the injection site. Enoxaparin (Lovenox) is available as a brand and generic medication.

• Prevention of blood clots in the arms or legs (deep vein thrombosis or DVT) or in the lungs (pulmonary embolism or PE) in:
  • People having stomach, hip, or knee surgery
  • People who aren't able to move well
  • People with a certain type of chest pain called unstable angina
• Treatment of blood clots
• Heart attack

• Abnormal liver tests (6%)
• Major bleeding (up to 4%)

• Risk of bleeding around the spinal cord during other injections near the spine
• Risk of bleeding
• Low platelet counts and clotting problems
• Higher risk of clots in pregnant women with prosthetic heart valves
• Risk of serious breathing problem in infants (gasping syndrome)

Xarelto (rivaroxaban) is a prescription blood thinner used to prevent and treat blood clots. It can lower the risk of serious problems like stroke, deep vein thrombosis (DVT), or pulmonary embolism (PE). It's comes as a tablet or liquid and is taken by mouth. Your dose depends on why you're taking it, so it could be once or twice a day. The most common side effect is bleeding, which can sometimes be serious or life-threatening. Xarelto (rivaroxaban) is available as both a brand-name and a generic medication.

Adults:

• Lower the risk of stroke and blood clots in people with atrial fibrillation (AFib) not caused by a heart valve problem
• Treat blood clots in the legs (deep vein thrombosis (DVT)) or lungs (pulmonary embolism (PE))
• Lower the risk of DVT or PE coming back after treatment
• Prevent DVT and PE after knee or hip replacement surgery
• Prevent blood clots in people in the hospital or recently released who are at high risk
• Lower the risk of serious heart problems, like heart attack or stroke, in people with coronary artery disease (CAD), taken with aspirin
• Lower the risk of blood clots and related problems in people with peripheral artery disease (PAD), taken with aspirin

Children:

• Treat blood clots and lower the risk of new clots in children from birth to under 18 years old
• Prevent blood clots in children 2 years and older with congenital heart disease (CHD) after a Fontan procedure

Adults

• Any bleeding (Up to 28%)

Children

• Any bleeding (36%)
• Cough (16%)
• Vomiting (14%)
• Stomach virus (13%)
• Rash (9%)

• Higher risk of blood clots if stopped too early
• Paralysis in the spine
• Bleeding
• Interactions with other medications
• Risk of pregnancy-related bleeding
• Not recommended in people with prosthetic heart valves
• Not recommended in people with antiphospholipid syndrome