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Lialda vs. Apriso

Mesalamine DR (Lialda) is an aminosalicylate that's used to treat mild-to-moderate ulcerative colitis (UC) in adults and children. It's a delayed-release (DR) tablet that's taken by mouth once daily with food. Side effects aren't common but can include headache and stomach upset. Mesalamine DR (Lialda) also has a risk for serious skin rash and sensitivity to the sun (e.g., might sunburn more easily).

• Mild-to-moderate ulcerative colitis (UC) in adults and children weighing at least 53 lbs

• Headache (3%)
• Stomach pain (2%)
• Diarrhea (2%)
• Abnormal liver enzyme levels (2%)

• Kidney damage and kidney stones
• Acute intolerance syndrome
• Severe allergic reactions
• Severe skin reactions
• Liver problems
• Caution in people with gut blockage
• Skin that's sensitive to sun and light

Mesalamine is used to help with an inflammatory bowel disease called ulcerative colitis (UC). It helps relieve symptoms of mild or moderate UC, such as stomach pain, diarrhea, and gut inflammation. This medication can also be used to maintain remission (prevent UC flare-ups) in adults. There are many brand names for mesalamine on the market, and they all have lower-cost generics available. The dosage depends on the brand and formulation of mesalamine you have. In general, this medication can cause side effects like headache and indigestion.

• Ulcerative colitis (UC)

• Headache
• Stomach pain
• Nausea
• Diarrhea
• Indigestion

• Kidney problems, including kidney stones
• Abnormal reaction to mesalamine
• Liver problems
• Allergic reactions and severe skin reactions
• Iron content in certain tablets and capsules of mesalamine
• Caution use in people with phenylketonuria (for Apriso extended-release capsules only)