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Keflex vs. Ceclor

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Cephalexin (generic name) and Cefaclor (generic name) are both cephalosporin antibiotics used to treat bacterial infections, but they have some differences. Cephalexin is a first-generation cephalosporin, while Cefaclor is a second-generation cephalosporin. Cephalexin is typically taken 2 to 4 times a day, whereas Cefaclor is taken 2 to 3 times a day. Cephalexin is available as capsules, tablets, and liquid suspensions, while Cefaclor comes in capsules, extended-release tablets, and liquid suspensions. Cephalexin is often used for respiratory tract infections, ear infections, skin infections, bone infections, UTIs, and reproductive system infections. Cefaclor is used for ear infections, lower respiratory tract infections, UTIs, strep throat, tonsil infections, and skin infections like cellulitis. Both medications can cause side effects like diarrhea and nausea, but Cefaclor can also cause headaches and runny nose. If you have a penicillin allergy, you might still be able to take either medication, but you should discuss this with your healthcare provider.

Cephalexin

 

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Cefaclor

 

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Summary for Keflex

Prescription only

Cephalexin, also commonly known as Keflex, is a cephalosporin antibiotic for people ages 1 year and older. It can treat many types of bacterial infections. This includes ear infections, skin infections like cellulitis, urinary tract infections (UTIs), and strep throat. Cephalexin comes as capsules, tablets, and a liquid suspension. It's taken by mouth 2 to 4 times per day. Side effects can include nausea, vomiting, and diarrhea. Cephalexin is a generic medication; its brand name Keflex is no longer available.

Indications for Keflex

Pros and Cons for Keflex

Pros

  • Treats several common types of bacterial infections
  • Okay for children as young as 1 year old to take
  • Available as a liquid for people who have trouble swallowing pills

Cons

  • Usually need to take a few times per day
  • Might not be able to take if you're allergic to penicillins or other cephalosporin antibiotics
  • Not recommended for the cold or flu (these are viral illnesses, not bacterial infections)

Common Side Effects for Keflex

  • Diarrhea
  • Nausea
  • Vomiting
  • Indigestion
  • Stomach pain

Warnings for Keflex

  • Allergic reactions
  • Diarrhea from Clostridioides difficile infection
  • Seizures
  • Higher risk of bleeding
  • Possible development of drug-resistant bacteria

Summary for Ceclor

Prescription only

Cefaclor is a second-generation cephalosporin antibiotic. It's used to treat many different types of infections throughout the body in both children and adults. This medication is available as tablets and as a liquid suspension that's taken by mouth, typically 2 to 3 times daily. Because cefaclor isn't a penicillin antibiotic, you might be able to take it if you have a penicillin allergy. Some side effects of cefaclor include headache, nausea, and diarrhea.

Indications for Ceclor

Pros and Cons for Ceclor

Pros

  • Treats many types of bacterial infections and has generally few side effects
  • Available as a capsule, extended-release tablet, and liquid suspension
  • Available as a lower-cost generic

Cons

  • Might not be able to take this medication if you've had a severe allergy to penicillins or other cephalosporin antibiotics
  • Needs to be taken 2 to 3 times a day
  • Liquid suspension must be stored in the refrigerator after mixing

Common Side Effects for Ceclor

  • Headache (5%)
  • Runny nose (4%)
  • Diarrhea (4%)
  • Nausea (3%)

Please note: These side effects were reported by people taking the cefaclor extended-release tablet.

Warnings for Ceclor

  • Severe allergic reactions
  • Infectious diarrhea
  • Difficult-to-treat infections

Prices with our coupons for Keflex vs. Ceclor

Price Card Drug Icon
Cephalexin28 capsules / 500mg
$10.68$29.90
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Price Card Drug Icon
Cefaclor30 capsules / 500mg
$41.11$139.69
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