Key takeaways
Ibuprofen (Advil, Motrin) and diclofenac (Cambia) are both nonsteroidal anti-inflammatory drugs (NSAIDs) used to relieve pain and inflammation, but they have some key differences. Ibuprofen is available over-the-counter and by prescription, while diclofenac is only available by prescription. Ibuprofen is commonly used for minor aches, fever, and conditions like arthritis, and it can be taken every 4 to 8 hours. Diclofenac, on the other hand, is used for more specific conditions like osteoarthritis, rheumatoid arthritis, and migraines, and its dosing varies depending on the formulation. Diclofenac comes in various forms, including delayed-release tablets and powder for oral solution, whereas ibuprofen is available in tablets, capsules, and liquid forms. Diclofenac is also available as a topical gel called Voltaren Arthritis Pain. Both medications have serious side effects, such as risks of heart attack, stroke, and stomach bleeding, but diclofenac has additional warnings for liver damage and high potassium levels. Lastly, diclofenac is not recommended for use in children, except for one specific formulation, while ibuprofen has formulations suitable for children.
