Key takeaways
Hydromorphone (Dilaudid) and oxycodone / acetaminophen (Percocet) are both opioid medications used to treat pain when non-opioid medications aren't effective. However, they differ in several ways. Hydromorphone is a single opioid medication, while Percocet is a combination of an opioid (oxycodone) and an analgesic (acetaminophen). Hydromorphone is available in various forms, including oral tablets, oral liquid, rectal suppositories, and an injection (only administered by a healthcare professional), whereas Percocet is available as oral tablets and oral liquid. Both medications are controlled substances with a high risk of misuse and dependence. Percocet also carries a risk of liver damage due to its acetaminophen content. Common side effects for both medicationsinclude constipation, drowsiness, and slowed breathing. It's important to avoid alcohol and other medications that can cause drowsiness with both medications, as this can result in severely slowed breathing. With Percocet, you should also avoid other acetaminophen-containing products to prevent liver damage.
