Key takeaways
Epzicom (abacavir/lamivudine) and Descovy (emtricitabine/tenofovir alafenamide) are both combination medications used to treat HIV, but they have some key differences. Epzicom is made up of abacavir and lamivudine, while Descovy contains emtricitabine and tenofovir alafenamide. They are both used with other HIV antiretrovirals for the treatment of HIV. Epzicom is taken once daily and is available in generic form, making it more affordable. However, it requires a genetic test before use due to the risk of a severe allergic reaction and is not recommended for people with heart problems. Descovy is also taken once daily and is preferred for HIV prevention (PrEP) but is not effective for females at risk through receptive vaginal sex. Unlike Epzicom, Descovy is safer for the kidneys and bones but requires regular blood tests to monitor kidney health. Both medications can worsen hepatitis B if stopped suddenly, so you should always consult your healthcare provider before making any changes.
