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Dymista vs. Flonase

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dymista (azelastine/fluticasone) and Flonase (fluticasone) are both nasal sprays used to treat allergy symptoms, but they have some key differences. Dymista is a combination of an antihistamine (azelastine) and a corticosteroid (fluticasone), while Flonase contains only a corticosteroid (fluticasone). Dymista is available by prescription only, whereas Flonase can be purchased over-the-counter (OTC) and also comes in a generic form. Dymista is typically used twice daily, while Flonase is usually used once daily. Dymista can start providing relief within 30 minutes, whereas Flonase may take several days to show benefits. Additionally, Dymista is approved for use in children as young as 6 years old, while Flonase Sensimist can be used in children as young as 2 years old. Both medications can cause side effects like nosebleeds and slowed growth in children, but Dymista may also cause drowsiness.

Dymista

(azelastine / fluticasone)

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fluticasone nasal spray

 

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Summary for Dymista

Prescription only

Dymista is a combination nasal spray containing azelastine (an antihistamine) and fluticasone (a corticosteroid). It's used by people ages 6 years and older to treat nasal allergy symptoms, such as runny, stuffy, or itchy nose. The typical dose is to spray one spray into each nostril twice per day. Side effects aren't common, but include headache and a bad taste in the mouth. Dymista (azelastine / fluticasone) is available as both brand-name and generic medications.

Indications for Dymista

  • Nasal allergy symptoms (e.g., runny, stuffy, or itchy nose, sneezing, itchy or watery eyes)

Pros and Cons for Dymista

Pros

  • Combines two medications into a single spray
  • Starts to work within 30 minutes after the first dose
  • Likely safe to use during pregnancy

Cons

  • Prescription only
  • Need to use daily for 2 weeks to experience the full effects of fluticasone in Dymista
  • Need to use twice per day

Common Side Effects for Dymista

Warnings for Dymista

  • Sleepiness
  • Nose bleeds, discomfort, and injury
  • Risk of infection
  • Altered stress hormone levels
  • Delayed growth in children
  • Allergic reactions
  • Eye and vision problems

Summary for Flonase

Prescription or over-the-counter

Fluticasone nasal spray is used to treat allergy symptoms, like runny nose and sneezing. Fluticasone nasal spray comes in brand and generic forms, and is available by a prescription or over-the-counter (OTC). Fluticasone nasal spray must be used daily in order for you to experience the maximum benefits. But if you're using OTC versions of this medication, don't use it for more than 6 months at a time (or 2 months at a time, for children) without first speaking to your provider.

Indications for Flonase

Nasal symptoms from allergies, such as:

  • Congestion
  • Runny nose
  • Sneezing
  • Itchy nose
  • Itchy, watery eyes

Pros and Cons for Flonase

Pros

  • Only has to be used once a day and can last up to 24 hours
  • Available OTC
  • Some formulations have generic versions
  • Can be used safely in children as young as 4 years old
  • Flonase Sensimist is a gentler version that can be used in children as young as 2 years old

Cons

  • Not a good option if you have an injured nose or had recent nasal surgery
  • Can raise the risk of bleeding and fungal infections in the nose
  • Can slow down growth rate in children if used for longer than 2 months per year
  • Can raise the risk for certain eye problems

Common Side Effects for Flonase

  • Headache (7-16%)
  • Sore throat (6-8%)
  • Nosebleeds (6-7%)
  • Asthma symptoms (3-7%)

Warnings for Flonase

  • Nasal problems
  • Slowed growth rate in children
  • Eye problems
  • Higher risk of infections
  • Stress hormone problems (adrenal gland problems)
  • Serious allergic reactions

Prices with our coupons for Dymista vs. Flonase

Price Card Drug Icon
Azelastine/Fluticasone1 nasal spray / 23g of 137mcg/50mcg
$47.39$155.11
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Fluticasone Propionate1 nasal spray / 16g of 50mcg
$14.67$47.00
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