Key takeaways
Pseudoephedrine (Sudafed) and triamcinolone (Nasacort) are both used to relieve nasal congestion, but they work in different ways and are used for different conditions. Pseudoephedrine is a decongestant taken orally to treat short-term nasal and sinus congestion from allergies and the common cold. It works by narrowing blood vessels in your nose and sinuses, which helps reduce congestion. On the other hand, triamcinolone is a corticosteroid nasal spray used to relieve symptoms of hay fever and allergies, such as sneezing, runny nose, and itchy nose. It works by reducing inflammation in your nasal passages. Pseudoephedrine is available in both immediate-release and extended-release forms, while triamcinolone is used once daily and can last up to 24 hours. Pseudoephedrine can cause side effects like anxiety and headaches and may raise your blood pressure, whereas triamcinolone might cause a sore throat or cough but is generally safer for people with high blood pressure. Both medications are available over-the-counter, but pseudoephedrine is restricted and must be purchased at the pharmacy counter.
