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Dymista vs. Astelin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dymista (azelastine/fluticasone) and azelastine nasal spray are both used to treat nasal allergy symptoms, but they have some key differences. Dymista is a combination of two medications: azelastine, an antihistamine, and fluticasone, a corticosteroid. This combination helps to block histamine and reduce inflammation, providing relief from symptoms like sneezing, runny nose, and itching. On the other hand, azelastine nasal spray contains only azelastine, which solely blocks histamine to relieve similar symptoms. Dymista is typically used when nasal steroid medications alone are not effective, while azelastine can be used for both seasonal and year-round allergies, as well as non-allergic nasal symptoms. Dymista is available only by prescription and must be used twice daily, whereas azelastine is available in both prescription and over-the-counter forms, with dosing that can vary. Additionally, Dymista may cause drowsiness and has a risk of stunting growth in children, while azelastine can cause a bitter taste and nasal discomfort. Both medications need to be primed before use and can cause sleepiness, so you should avoid activities that require alertness until you know how they affect you.

Dymista

(azelastine / fluticasone)

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azelastine nasal spray

 

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Summary for Dymista

Prescription only

Dymista is a combination nasal spray containing azelastine (an antihistamine) and fluticasone (a corticosteroid). It's used by people ages 6 years and older to treat nasal allergy symptoms, such as runny, stuffy, or itchy nose. The typical dose is to spray one spray into each nostril twice per day. Side effects aren't common, but include headache and a bad taste in the mouth. Dymista (azelastine / fluticasone) is available as both brand-name and generic medications.

Indications for Dymista

  • Nasal allergy symptoms (e.g., runny, stuffy, or itchy nose, sneezing, itchy or watery eyes)

Pros and Cons for Dymista

Pros

  • Combines two medications into a single spray
  • Starts to work within 30 minutes after the first dose
  • Likely safe to use during pregnancy

Cons

  • Prescription only
  • Need to use daily for 2 weeks to experience the full effects of fluticasone in Dymista
  • Need to use twice per day

Common Side Effects for Dymista

Warnings for Dymista

  • Sleepiness
  • Nose bleeds, discomfort, and injury
  • Risk of infection
  • Altered stress hormone levels
  • Delayed growth in children
  • Allergic reactions
  • Eye and vision problems

Summary for Astelin

Prescription only

Azelastine nasal spray is an antihistamine that treats allergies and nasal symptoms, such as runny or stuffy nose. The 0.1% and 0.15% strengths of the azelastine nasal spray are available with a prescription for adults and children. It's sprayed into the nostrils typically twice a day. Prescription azelastine nasal spray is a lower-cost generic. Possible side effects include a bitter taste in the mouth and nasal discomfort.

Note: Azelastine 0.15% nasal spray is also available over the counter under the brand name Astepro Allergy.

Indications for Astelin

  • Seasonal allergy symptoms related to the nose
  • Year-round allergy symptoms related to the nose - azelastine 0.15% spray only
  • Runny or stuffy nose that isn't caused by allergies - azelastine 0.1% spray only

Pros and Cons for Astelin

Pros

  • Works well to relieve nasal symptoms during allergy season
  • Might work faster than steroid nasal sprays and some oral antihistamines
  • Sprayed directly into the nose
  • Available in two different strengths (0.1% and 0.15%)

Cons

  • Doesn't have a counter to keep track of the number of sprays you have left in the bottle
  • Can leave a bitter taste in your mouth (but it goes away)
  • Can cause sleepiness in some people
  • Might need to use twice a day

Common Side Effects for Astelin

Azelastine 0.1% nasal spray:

  • Bitter taste in the mouth (20%)
  • Headache (15%)
  • Sleepiness (12%)
  • Nasal burning (4%)

Azelastine 0.15% nasal spray:

  • Bitter taste in the mouth (4%)
  • Nasal discomfort (4%)

Warnings for Astelin

  • Possible sleepiness and difficulty concentrating

Prices with our coupons for Dymista vs. Astelin

Price Card Drug Icon
Azelastine/Fluticasone1 nasal spray / 23g of 137mcg/50mcg
$47.39$155.11
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Price Card Drug Icon
Azelastine1 nasal spray / 30ml of 137mcg/spray
$19.97$33.36
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