Key takeaways
Cyclobenzaprine (Flexeril) and oxycodone (Roxicodone, Oxaydo) are both medications used to manage pain, but they belong to different classes and have distinct uses. Cyclobenzaprine is a muscle relaxant that helps relieve muscle spasms and discomfort, while oxycodone is an opioid used for pain that isn't relieved by non-opioid medications. Cyclobenzaprine is available as immediate-release tablets and extended-release capsules, and it's typically taken for short-term use, up to 2 to 3 weeks. Oxycodone, on the other hand, is available as immediate-release tablets, capsules, and liquid, and is taken every 4 to 6 hours as needed. Cyclobenzaprine is not a controlled substance, whereas oxycodone is a Schedule II controlled substance due to its high risk of misuse and dependence. Common side effects of cyclobenzaprine include drowsiness and dry mouth, while oxycodone can cause constipation, nausea, and dizziness. Both medications can cause drowsiness, so you should avoid alcohol and be cautious with activities that require focus. Both medications can interact with antidepressants, leading to serotonin syndrome, and medications that cause drowsiness, increasing the risk of dangerous side effects.
