Key takeaways
Loratadine (Claritin) and levocetirizine (Xyzal) are both antihistamines used to relieve allergy symptoms, but they have some differences. Loratadine is available over-the-counter and is less likely to cause drowsiness compared to levocetirizine. Levocetirizine can be obtained both over-the-counter and by prescription and is known to work a bit faster than loratadine. However, levocetirizine is not recommended for people with severe kidney problems. Loratadine is generally taken once daily and is available in various forms, including tablets and liquids, while levocetirizine also comes in tablets and liquid but is typically taken in the evening. Neither medication should be combined with other antihistamines to avoid serious side effects.
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