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Carisoprodol vs. Cyclobenzaprine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Carisoprodol (Soma) and cyclobenzaprine (Flexeril) are both muscle relaxants used to treat muscle pain and discomfort. They are similar in that they are both prescribed for short-term relief of muscle-related conditions. However, they differ in several ways. Carisoprodol is a controlled substance due to its potential for misuse and dependence, while cyclobenzaprine is not. Carisoprodol is typically taken four times a day, whereas cyclobenzaprine is available in both immediate-release (taken three times a day) and extended-release forms (taken once a day). Both medications are available as a lower-cost generic and can cause drowsiness, dizziness, and headaches. Cyclobenzaprine may not be a good option for those over age 65 years or with liver problems. You should avoid drinking alcohol while taking either medication.

Carisoprodol

(Soma)

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Cyclobenzaprine

 

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Summary for Carisoprodol

Prescription only

Carisoprodol (Soma) is a muscle relaxant that's used to treat muscle pain and discomfort in people ages 16 to 64. The tablets are approved for short-term treatment only and should only be taken for up to 2 to 3 weeks. Researchers think the medication relaxes muscles by changing nerve activity in your nervous system. Carisoprodol (Soma) is a controlled substance because it has a risk for misuse and dependence. Common side effects include headaches, dizziness, and sleepiness.

Indications for Carisoprodol

  • Discomfort caused by painful muscle-related conditions (short-term only)

Pros and Cons for Carisoprodol

Pros

  • Works quickly (generally within 30 minutes) to relieve muscle pain and discomfort
  • Available in two different strengths
  • Available as a lower-cost generic

Cons

  • Not a first-choice option for muscle pain
  • Typically taken four times daily
  • Can be habit-forming
  • Unknown if it's safe for people younger than age 16 or older than age 65

Common Side Effects for Carisoprodol

  • Drowsiness (13-17%)
  • Dizziness (7-8%)
  • Headache (3-5%)

Warnings for Carisoprodol

  • Extreme sleepiness and trouble with concentration
  • Risk for misuse, dependence, and withdrawal
  • Seizures

Summary for Cyclobenzaprine

Prescription only

Cyclobenzaprine is a muscle relaxant that helps relieve muscle pain and discomfort. It's often used short term with rest and physical therapy. Immediate-release tablets are for people 15 years and older and are taken a few times a day. Once sold under the brand name Flexeril, the tablets now as a generic and brand name Fexmid. Extended-release capsules are for adults only and are taken once a day. The capsules comes as a generic and brand name Amrix. Cyclobenzaprine can make you sleepy and have dry mouth as side effects.

Indications for Cyclobenzaprine

  • Muscle discomfort from short-term muscle or bone injury problems

Pros and Cons for Cyclobenzaprine

Pros

  • Can take with or without food
  • Available as short-acting and long-acting forms for flexible dosing schedules
  • Can help with recovery from acute painful muscle problems in a few days

Cons

  • Only meant for short-term use (up to 2 to 3 weeks at a time)
  • Might not be a safe option for older adults
  • Not known to work well for nerve pain or muscle spasms caused by brain or spinal injuries

Common Side Effects for Cyclobenzaprine

Immediate-release tablets:

  • Drowsiness (39%)
  • Dry mouth (27%)
  • Dizziness (11%)

Extended-release capsules:

  • Dry mouth (14%)
  • Dizziness (6%)

Warnings for Cyclobenzaprine

  • Serotonin syndrome
  • Effect on driving and concentration
  • Caution use in people with glaucoma or trouble urinating
  • Caution use in people with liver problems

Prices with our coupons for Carisoprodol vs. Cyclobenzaprine

Price Card Drug Icon
Carisoprodol60 tablets / 350mg
$9.25$39.99
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Cyclobenzaprine30 tablets / 10mg
$8.90$30.69
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