Key takeaways
Augmentin (amoxicillin/clavulanate) and Bactrim (sulfamethoxazole/trimethoprim) are both antibiotics used to treat bacterial infections, but they belong to different drug classes and work in different ways. Augmentin is a combination of a penicillin antibiotic and a beta-lactamase inhibitor, which helps prevent bacteria from breaking down the antibiotic. It is commonly used for respiratory tract infections, ear infections, sinus infections, and UTIs, and is available in tablet, chewable tablet, and liquid forms. Bactrim, on the other hand, combines a sulfonamide antibiotic with an antifolate, which stops bacteria from making folic acid. It treats UTIs, ear infections, and certain types of pneumonia, and comes in tablet, liquid, and injection forms. Augmentin is safe to use during pregnancy, while Bactrim is not recommended for pregnant individuals. Both medications can cause side effects like nausea and diarrhea, but Bactrim can also make your skin more sensitive to the sun. Additionally, Augmentin should be avoided if you have a penicillin allergy, whereas Bactrim should not be used if you have a sulfa allergy.
