Admelog vs. Fiasp for Diabetes Type 2 and Diabetes Type 1: Important Differences and Potential Risks.

Admelog

(insulin lispro)

Fiasp

(Insulin aspart)

Summary for Admelog

Prescription only

Admelog (insulin lispro) is a fast-acting insulin that's used at mealtimes. It helps control blood sugar levels from food in adults and children with Type 1 diabetes or Type 2 diabetes. Admelog (insulin lispro) is very similar to Humalog (insulin lispro). It's called a "follow-on" insulin (or "copy") to Humalog. Admelog (insulin lispro) is usually given under the skin as an injection or through an insulin pump. It comes in vials (Admelog) or prefilled pens (Admelog SoloStar). The most common side effect is low blood sugar (hypoglycemia).

Indications for Admelog

Type 1 diabetes (T1D) in people ages 3 years and older
Type 2 diabetes (T2D) in adults

Pros and Cons for Admelog

Pros

Starts to lower blood sugar levels about 15 to 30 minutes after each injection
Available as a prefilled pen, which can be easier to use than the vial
Can be used with an appropriate continuous insulin infusion pump

Cons

Should be given with every meal, if using as mealtime insulin
Can put you at risk of low blood sugar if not used properly or if the dose is too high
Might cause weight gain

Common Side Effects for Admelog

Low blood sugar

Warnings for Admelog

Risk of infections from sharing injection supplies
Risk of too high or too low blood sugar with changes to your insulin regimen
Low blood sugar levels (hypoglycemia)
Allergic reactions
Low potassium levels
Swelling and risk of heart failure when used with certain diabetes medications
Dangerously high blood sugar levels and ketoacidosis due to insulin pump problems

Summary for Fiasp

Prescription only

Fiasp (Insulin aspart) is a fast-acting insulin. It helps control blood sugar levels in adults and children with type 1 diabetes (T1D) or type 2 diabetes (T2). It's similar to insulin apart (Novolog), but it works more quickly because it contains niacinamide and L-arginine, which help with absorption. Fiasp comes as a vial, Fiasp Flextouch pen, Fiasp PenFill cartridge, and Fiasp PumpCart cartridge. This medication is given as an injection under the skin or through a continuous insulin pump. Some common side effects include upper respiratory tract infections and the common cold.

Indications for Fiasp

Type 1 diabetes (T1D) in adults and children ages 2 years and older
Type 2 diabetes (T2D) in adults

Pros and Cons for Fiasp

Pros

Starts to work within 20 minutes to control your blood sugar levels after meals
Can be used in people with liver or kidney problems, unlike other oral diabetic medications
Available as a vial, pen, and cartridges for insulin pumps
An option for children

Cons

Given as an injection
Higher risk of low blood sugar compared to diabetes medications that are taken by mouth
Needs to be given multiple times per day
Must be used with every meal

Common Side Effects for Fiasp

Adults:

Common cold (20-24%)
Respiratory tract infection (7-9%)
Urinary tract infection (6%)
Nausea (5%)
Back pain (4-5%)
Diarrhea (3-5%)

Children:

Respiratory tract infections (8-23%)
Flu (6-8%)
Runny nose (4-6%)
Headache (6-10%)
Fever (6-8%)
Vomiting (3-8%)

Warnings for Fiasp

Spread of infections from sharing injection supplies
Risk of high and low blood sugar levels
Dangerously low blood sugar levels (hypoglycemia)
Low blood potassium levels
Swelling from fluid buildup and risk of heart failure when taken with certain blood sugar medications
Dangerously high blood sugar levels or buildup of ketones (for people who use insulin pump)