Key takeaways
Novolin N (insulin NPH) and Apidra (insulin glulisine) are both insulins used to manage blood sugar levels in people with Type 1 and 2 diabetes, but they have some key differences. Novolin N is an intermediate-acting insulin that works throughout the day and is typically injected once or twice daily under the skin. It’s available both by prescription and over the counter. In contrast, Apidra is a rapid-acting insulin that starts working within 15 minutes and is usually taken before or right after meals. Apidra is a prescription medication available in a vial or pre-filled pen injected under the skin. It can also be used in an insulin pump or given through an IV in a hospital setting. Novolin N can be mixed with other insulins, such as insulin regular (Novolin R) and Apidra, whereas Apidra can only be mixed with Novolin N. Both medications are only available as brand name and can cause low blood sugar and weight gain.
