
cefadroxil
Cefadroxil is an antibiotic that can treat many types of bacterial infections in adults and children. This includes urinary tract infections (UTIs), strep throat, and skin infections. Cefadroxil works as a first-generation cephalosporin antibiotic to fight the infection. It comes as generic capsules, tablets, and a liquid suspension. The antibiotic is taken by mouth, usually once or twice a day. But the dosage depends on the type of infection you have, how serious it is, and for children, weight. Side effects can include diarrhea, indigestion, and nausea.
What is Cefadroxil?
What is Cefadroxil used for?
- Urinary tract infections (UTIs)
- Skin infections (e.g., cellulitis)
- Strep throat
- Tonsillitis
How Cefadroxil works
Cefadroxil is a cephalosporin antibiotic. It works by stopping bacteria from making a protective covering around themselves. This kills the bacteria and helps treat the infection.
Drug facts
| Common Brands | Duricef |
|---|---|
| Drug Class | Cephalosporin antibiotic |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | Lower-cost generic available |
| Availability | Prescription only |
Side effects of Cefadroxil
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Diarrhea
- Indigestion
- Nausea
- Vomiting
Less Common Side Effects
- Itching
- Joint pain
- Fever
Cefadroxil serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions: hives; rash; blisters; peeling skin; swelling of the lips, tongue, or face; trouble breathing
- Infectious diarrhea (C. difficile-related diarrhea): fever, nausea, foul-smelling diarrhea, frequent bowel movements (up to 15 times per day)
The following Cefadroxil side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Rare
Black, tarry stools
bleeding gums
blistering, peeling, or loosening of the skin
blood in the urine or stools
chills
clay-colored stools
cough or hoarseness
dark-colored urine
difficulty with moving
feeling of discomfort
fever with or without chills
flushing or redness of the skin
general feeling of tiredness or weakness
headache
inflammation of the joints
joint or muscle pain
light-colored stools
lower back or side pain
muscle aches
muscle pain or stiffness
painful or difficult urination
pinpoint red spots on the skin
rash
red skin lesions, often with a purple center
red, irritated eyes
sores, ulcers, or white spots on the lips or in the mouth
stomach pain, continuing
swollen lymph glands
unusual bleeding or bruising
unusually warm skin
vomiting
yellow eyes or skin
Incidence not known
Abdominal or stomach cramps or tenderness
back, leg, or stomach pains
coughing up blood
diarrhea, watery and severe, which may also be bloody
difficulty with breathing or swallowing
dizziness
fast heartbeat
general body swelling
high fever
increased menstrual flow or vaginal bleeding
increased thirst
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
loss of appetite
nosebleeds
pale skin
paralysis
prolonged bleeding from cuts
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
seizures
shortness of breath
sudden decrease in the amount of urine
swollen or painful glands
tightness in the chest
unpleasant breath odor
unusual tiredness or weakness
unusual weight loss
vomiting of blood
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Pros and cons of Cefadroxil
Pros
- Treats many types of bacterial infections
- Taken once or twice a day, with or without food
- Also available as a liquid suspension for people who have trouble swallowing pills
Cons
- Not recommended to be used for the cold or flu (since these are viral illnesses)
- Might not be a good option if you have gut inflammation or other digestive tract problems
- Might not be able to take if you're allergic to penicillins or other cephalosporin antibiotics
Pharmacist tips for Cefadroxil
- Take cefadroxil exactly as your prescriber instructed you to. It's important to finish your treatment course, even if you start feeling better. Stopping too early can make your infection come back and become harder to treat.
- You can take cefadroxil with or without food. If it causes stomach upset, try taking it with food next time. This might help calm your stomach. But be sure to avoid spicy or acidic foods because these can make stomach upset more likely.
- Swallow the cefadroxil tablet or capsule whole. Don't crush or chew it because it might damage the medication. If you have trouble swallowing pills whole, ask your prescriber if you can take the liquid version of the antibiotic instead.
- Cefadroxil can cause mild diarrhea that usually goes away after you stop taking it. But pay attention to severe diarrhea. This can look like watery or bloody stools, very frequent diarrhea, fever, or stomach cramps during or after treatment. Get medical help right away because these can be signs of serious infectious diarrhea.
- Get urgent medical care if you have a rash, itchy or peeling skin, trouble breathing, or swelling of your face or mouth. These might be signs of a serious allergic reaction to cefadroxil.
- It's a good idea to avoid drinking alcohol while taking cefadroxil. Alcohol can make side effects like nausea and vomiting worse. It can also slow recovery from your infection. Talk to your prescriber or care team about your drinking habits and how to take this antibiotic in a safe way.
For the cefadroxil liquid suspension:
- The pharmacist will mix the cefadroxil liquid for you when you pick up your medication. They'll also give you a medication dose cup or oral syringe to help measure each dose.
- Shake the bottle of cefadroxil well before each dose. This helps mix the medication well so you get the right amount of medication when you measure your dose.
- Measure the cefadroxil liquid with a dosing cup or oral syringe. Don't use kitchen spoons because they aren't accurate and could cause you to take the wrong dose.
- Keep the cefadroxil liquid in the refrigerator for up to 14 days. After that time, throw it away, even if some medication is left inside the bottle.
Risks and warnings for Cefadroxil
Cefadroxil can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Allergic reactions
- Risk factors: Allergy to penicillin or other cephalosporin antibiotics
Some people can have allergic reactions to cefadroxil. Mild reactions can include a rash or hives. More serious, life-threatening reactions can include blisters, peeling skin, swelling of the face, and anaphylaxis.
Tell your healthcare team if you're allergic to any antibiotics, especially penicillins or other cephalosporins. They can make sure cefadroxil is safe for you.
Get medical help right away if you have a rash, hives, red or peeling skin, swelling of the lips or tongue, or trouble breathing after taking cefadroxil. These can be signs of an allergic reaction.
Diarrhea from Clostridioides difficile infection
Antibiotics including cefadroxil can change the normal bacteria in your gut. This can let harmful bacteria called Clostridioides difficile (C. diff) grow too much and cause a serious infection. This infection can lead to severe diarrhea, even up to 2 months after you stop the antibiotic.
It's important to know the difference between mild diarrhea from cefadroxil and serious diarrhea from C. diff. Signs of a C. diff infection include fever, nausea, foul-smelling diarrhea, and frequent bowel movements. Get medical help right away if you have any signs of this infectious diarrhea. This can be a medical emergency and should get treated as soon as possible.
Seizures
- Risk factors: Kidney problems | Taking high doses of cefadroxil
Antibiotics like cefadroxil might raise the risk of seizures. The risk is high if you have kidney problems and the cefadroxil dose isn't lowered enough for you. When the kidneys don't work well, the medication can build up in the body and raise the risk of side effects, including seizures.
Tell your prescriber or the urgent care team if you've had seizures before or if you have kidney problems. They can make sure that cefadroxil is safe for you. If you have a seizure while taking this medication, get medical help right away.
Possible development of drug-resistant bacteria
Take cefadroxil exactly as your prescriber told you. Don't take it for a shorter or longer time, and don't take it for other illnesses. Otherwise, it can raise your risk of developing infections caused by drug-resistant bacteria. These infections can be very serious and harder to treat.
Cefadroxil dosage
Typical dosage for Cefadroxil
-
Adults
- Urinary tract infection: The typical dose is 1 to 2 grams by mouth per day. This dose is taken once a day, or it's split into equal doses and taken two times a day. The specific dose will depend on the type of urinary tract infection you have.
- Skin infection: The typical dose is 1 gram by mouth once a day, or 500 mg by mouth twice a day.
- Strep throat or tonsillitis: The typical dose is 1 gram by mouth once a day, or 500 mg by mouth twice a day, for 10 days.
-
Children
- Urinary tract infection: The dose is based on your child's body weight. The typical dose is 15 mg/kg by mouth every 12 hours.
- Skin infection: The dose is based on your child's body weight. The typical dose is 15 mg/kg by mouth every 12 hours. If it's for impetigo, your child might be prescribed 30 mg/kg once a day.
- Strep throat or tonsillitis: The dose is based on your child's body weight. The typical dose is 30 mg/kg by mouth once a day, or 15 mg/kg by mouth every 12 hours.
Your dose might differ if you have kidney problems.
Interactions between Cefadroxil and other drugs
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Cholera Vaccine, Live
- Desogestrel
- Dienogest
- Drospirenone
- Estradiol
- Ethinyl Estradiol
- Ethynodiol
- Gestodene
- Levonorgestrel
- Mestranol
- Nomegestrol
- Norethindrone
- Norgestimate
- Norgestrel
- Warfarin
How much does Cefadroxil cost?
$13.93
Cefadroxil contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Cefadroxil will not be safe for you to take.
- Known allergy to other cephalosporin antibiotics
What are alternatives to Cefadroxil?
News about Cefadroxil

