The GoodRx Prescription Savings Blog

The latest updates on prescription drugs and ways to save from the GoodRx medical team

Embeda Is Back: New Pain Med with Improved Safety

by The GoodRx Pharmacist on October 31, 2014 at 11:22 am

Embeda is a schedule II extended-release narcotic used for the management of severe pain that requires daily, around-the-clock treatment on a long-term basis. It contains extended-release morphine as well as the abuse deterrent naltrexone.

The new formulation of Embeda has properties that are expected to reduce, but not totally prevent, abuse of the medication. Naltrexone is thought to prevent the euphoric effect of the medication if it is crushed, chewed, or dissolved for snorting or injecting. Naltrexone can also cause withdrawal symptoms in persons addicted to opioids. However, it is unknown if the abuse-deterrent properties of Embeda will significantly decrease abuse until post marketing data is available.

When was Embeda first approved?

The FDA first approved this medication on August 13, 2009.

Why was Embeda withdrawn from the market?

The manufacturer, Pfizer, voluntarily recalled then withdrew Embeda from the market in March 2011 due to concerns regarding stability in the making of the medication.

When will Embeda be available again?

According to the manufacturer, this medication will return to the market in early 2015. Embeda was approved by the FDA on October 17, 2014 as the third extended-release opioid pain reliever with approved labeling for its abuse-deterrent features.

What is the difference between Embeda and current extended-release morphine products?

The new formulation of Embeda contains abuse-deterrent features to help eliminate the potential for abuse when taken by mouth or snorted. In this case, abuse can mean (but isn’t limited to) crushing, snorting, or injecting a medication that is intended for extended-release absorption.

The other extended-release morphine products that are currently available (Avinza, Kadian, MS Contin) DO NOT contain abuse-deterrent features.

How is Embeda taken?
Embeda is available as an extended-release capsule in the following strengths: 20 mg/0.8 mg, 30 mg/1.2 mg, 50 mg/2 mg, 60 mg/2.4 mg, 80 mg/3.2 mg, 100 mg/4 mg.

Embeda is taken every 24 hours and is NOT to be used on an as needed basis.

More information on Embeda:

There is not an official Embeda website at this time, but more information for healthcare professionals can be found here.

Copyright ©2015 GoodRx, Inc.

This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment. Third party logos, trademarks, brand names and images contained on are for demonstration purposes only and are owned by their respective rights holders, who are not affiliated with this Site.