provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content
Amjevita Coupon - Amjevita 2 autoinjectors of 40mg/0.4ml carton

Amjevita

adalimumab-atto
Used for Plaque Psoriasis, Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Crohn's Disease, Ankylosing Spondylitis, Hidradenitis Suppurativa, Juvenile Idiopathic Arthritis, Uveitis
Used for Plaque Psoriasis, Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Crohn's Disease, Ankylosing Spondylitis, Hidradenitis Suppurativa, Juvenile Idiopathic Arthritis, Uveitis

Amjevita, the brand name for adalimumab-atto, is an injectable medication that treats many different autoimmune and inflammatory conditions, including rheumatoid arthritis (RA) psoriatic arthritis (PsA), and Crohn's disease (CD). Although the medication is a biosimilar to Humira (adalimumab), it's not yet FDA approved to treat all age groups for some of the conditions Humira (adalimumab) is approved for. The typical dosing is one injection given under the skin every other week. Common side effects include infections and injection site reactions.

Last reviewed on December 9, 2024
basics-icon

What is Amjevita (adalimumab-atto)?

What is Amjevita (adalimumab-atto) used for?

How Amjevita (adalimumab-atto) works

Amjevita (adalimumab-atto) is a tumor necrosis factor (TNF) blocker. It works by blocking TNF, a protein in your body that plays a role in inflammation. By stopping TNF, the medication helps lower inflammation and relieve symptoms in various parts of the body.

Are you looking for information on Humira (adalimumab) instead?

Drug Facts

Common BrandsAmjevita
Drug ClassTNF blocker
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
coupon-save-icon

Get your GoodRx coupon

Avg retail price
$1819.54(save 24.68%)
GoodRx discount
$1370.45
See prices
basics-icon

What are the side effects of Amjevita (adalimumab-atto)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Injection site reaction (20%)
  • Upper respiratory tract infection (17%)
  • Headache (12%)
  • Rash (12%)
  • Sinus inflammation (11%)
  • Accidental injury (10%)
  • Nausea (9%)
  • Urinary tract infection (UTI) or bladder infection (8%)

Other Side Effects

  • High cholesterol
  • High blood pressure
  • Back pain
  • Stomach pain
  • Hair loss
  • Blood in the urine
  • Flu-like symptoms
Note: Side effects reported above are from studies with Humira (adalimumab)

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Serious infection: fever, cough, weight loss, muscle aches, dark urine, chills, vomiting
  • Low blood cell counts: fever that doesn't go away, easy bruising or bleeding, pale skin
  • Severe allergic reaction: rash, trouble breathing, swelling of your face, eyes, lips, or mouth, hives
  • Heart failure: shortness of breath, swelling in the legs, ankles, or feet, irregular heartbeat, tiredness, sudden weight gain
  • Liver problems: feeling tired, vomiting, yellow skin or whites of the eyes, stomach pain, poor appetite

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Body aches or pain

cough

ear congestion

gas with stomach pain

hoarseness

lightheadedness

loss of voice

lower back or side pain

muscle aches and pains

pain or tenderness around the eyes or cheekbones

rapid and sometimes shallow breathing

shivering

stomach fullness

stuffy nose

sunken eyes

thirst

trouble sleeping

warmth on the skin

wrinkled skin

Less common

Abnormal vaginal bleeding or discharge

agitation

arm, back, or jaw pain

black, tarry stools

bleeding from the gums or nose

blindness

bloating or swelling of the face, arms, hands, lower legs, or feet

blood in the stool or change in bowel habits

bloody or cloudy urine

blurred vision

broken bones

change in size, shape, or color of an existing mole

change in skin color

chest pain, tightness, or heaviness

chills

clear or bloody discharge from the nipple

cold hands and feet

confusion

constipation

cough

coughing or spitting up blood

decreased urination

decreased vision

depression

difficulty with breathing

difficulty, burning, or painful urination

dimpling of the breast skin

dizziness

drowsiness

eye pain

fainting

fast, slow, or irregular heartbeat

fever

forgetfulness

frequent urge to urinate

general feeling of illness

hair loss

headache

hives, itching, skin rash

increased thirst

inverted nipple

irregular breathing

irregular pulse

irritability

light colored stools

loss of appetite

lump in the breast or under your arm

lump or swelling in the stomach

mole that leaks fluid or bleeds

muscle cramps or spasms

nausea

new mole

night sweats

no blood pressure or pulse

noisy breathing

numbness or tingling in your arms, legs, or face

pain, redness, or swelling in the arms or legs without any injury present

pale skin

persistent non-healing sore on your skin

pink growth

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

raised, firm, or bright red patch

redness or swelling of the breast

seeing or hearing things that are not there

seizures

sharp back pain just below your ribs

shiny bump on your skin

slurred speech or problems with swallowing

sneezing

sore on the skin of the breast that does not heal

sore throat

sores, ulcers, or white spots on the lips or mouth

spitting up blood

stiff neck

stomach pain

stopping of the heart

sudden high fever or low grade fever for months

sweating

swelling of the face, fingers, feet, or lower legs

swollen glands

swollen neck veins

tiredness

trouble breathing

trouble thinking

unconsciousness

unexplained bruising or bleeding

unpleasant breath odor

unusual tiredness or weakness

unusual weight gain or loss

visual disturbances

vomiting

vomiting of blood or material that looks like coffee grounds

yellow skin or eyes

Incidence not known

Blistering, peeling, or loosening of the skin

diarrhea

inability to move the arms and legs

joint or muscle pain

pinpoint red spots on the skin

red skin lesions, often with a purple center

red, irritated eyes

red, scaling, or crusted skin

sudden numbness and weakness in the arms and legs

unusual bleeding or bruising

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Bladder pain

bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

pounding in the ears

Less common

Abnormal healing

decrease in height

difficulty with moving

difficulty with walking

dry mouth

heartburn

indigestion

loss of hearing

loss of strength or energy

menstrual changes

muscle or joint stiffness, tightness, or rigidity

muscle pain or weakness

pain in the back, ribs, arms, or legs

shakiness in the legs, arms, hands, and feet

swelling or redness in the joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Amjevita (adalimumab-atto)

thumbs-up

Pros

Works to treat many different autoimmune conditions

Can be given at home (if your prescriber says it's safe to do so)

Only needs to be injected a few times per month

Conveniently available as a prefilled syringe or autoinjector

Not made with natural rubber latex, which is good for people with allergies

thumbs-down

Cons

Raises the risk for serious infections

Can take weeks to months to notice symptom improvement

Must avoid live vaccines while taking the medication

Only manages symptoms, doesn't cure the condition

Not known if it's safe in pregnancy or breastfeeding

pharmacist-tips

Pharmacist tips for Amjevita (adalimumab-atto)

pharmacist
  • If you miss a dose of Amjevita (adalimumab-atto), inject it as soon as you remember. Then, continue with your regular injection schedule.

    • Before using Amjevita (adalimumab-atto) at home, you should receive injection training from your prescriber or care team. If you haven't, contact the clinic or your pharmacist. Don't try to give yourself an injection until you're comfortable doing it safely and properly.

      • Store unused Amjevita (adalimumab-atto) in the refrigerator. If refrigeration isn't available or you're traveling, you can keep it at room temperature for up to 14 days. Throw it away after 14 days at room temperature, as it might not work properly anymore.

        • Throw away used needles, syringes, and autoinjectors in a sharps container to prevent needlestick injuries. Check your local laws and guidelines for how to dispose of your container once it's almost full.

          • Amjevita (adalimumab-atto) can weaken your immune system, making it harder to fight infections. Let your prescriber know if you experience symptoms of an infection like fever, muscle aches, shortness of breath, cough, or fatigue.

            • You can get some vaccines while taking Amjevita (adalimumab-atto), but avoid live vaccines, as it’s not clear how they interact with this medication. Make sure your child is up to date on their vaccines before starting Amjevita (adalimumab-atto). And talk to your prescriber before getting any vaccines.

              How to inject Amjevita (adalimumab-atto):

              • When ready for your injection, take Amjevita (adalimumab-atto) out of the refrigerator and let it warm up to room temperature for about 15 to 30 minutes. This will help reduce discomfort with the injection. Never try to warm it up by putting it in the microwave or in hot water.

                • Wash your hands with soap and water and clean your chosen injection site with an alcohol swab before injecting Amjevita (adalimumab-atto). This will help prevent infection.

                  • Inject Amjevita (adalimumab-atto) under the skin in the front of your thighs or at least 2 inches away from your belly button if injecting in your stomach area. Be sure to rotate injection sites each time to allow your skin to heal.

                    faqs

                    Frequently asked questions about Amjevita (adalimumab-atto)

                    Does Amjevita (adalimumab-atto) cause acne?
                    Not normally. Amjevita (adalimumab-atto) doesn't typically cause acne. If you notice acne after starting this medication and are concerned, talk to your prescriber.
                    How do you inject Amjevita (adalimumab-atto)?
                    You can inject Amjevita (adalimumab-atto) under the skin either on the front of your thighs or your stomach. If you inject it into your stomach, make sure the area is at least 2 inches away from your belly button. Rotate your injection sites each time to allow your skin to heal. And avoid injecting the medication into skin that's red, bruised, or broken.
                    Is Amjevita (adalimumab-atto) citrate free?
                    Yes, Amjevita (adalimumab-atto) is citrate-free. Citrate is an ingredient sometimes found in injectable medications. Studies have shown that injections containing citrate might cause more pain than those without.
                    Is Amjevita (adalimumab-atto) the same as Humira (adalimumab)?
                    Amjevita (adalimumab-atto) is a biosimilar to Humira (adalimumab), meaning it has a comparable structure and works similarly to Humira. Biosimilars aren't identical to the original biologic. Although both medications treat similar autoimmune and inflammatory conditions, Amjevita (adalimumab-atto) isn't FDA approved for all age groups that Humira (adalimumab) covers. For example, Humira (adalimumab) is approved to treat uveitis (UV) in children and adults, but Amjevita (adalimumab-atto) is only approved for adults. Amjevita (adalimumab-atto) isn't interchangeable with Humira, so a new prescription is needed to switch between them.
                    How long does it take Amjevita (adalimumab-atto) to work?
                    It might take Amjevita (adalimumab-atto) a few weeks to work. And it can take months to see the full effects. Your results will depend on why you're taking the medication, how bad your symptoms are, and how well you respond to the treatment. Discuss with your prescriber when you should expect to notice an improvement in your symptoms after starting Amjevita (adalimumab-atto).
                    Does Amjevita (adalimumab-atto) cause weight gain?
                    Weight gain isn't a common side effect of Amjevita (adalimumab-atto). But sudden weight gain can be a sign of heart failure, which has been rarely reported with similar medications. Speak with your prescriber if you experience weight gain with this medication.
                    Can Amjevita (adalimumab-atto) cause liver damage?
                    Although rare, TNF blockers like Amjevita (adalimumab-atto) have been linked to liver damage. Most cases have been mild and often without symptoms. Since some people in studies were also taking other medications that can harm the liver, more research is needed to understand how Amjevita (adalimumab-atto) affects the liver. Before starting this medication, your prescriber will check for a history of hepatitis B, as the virus can become active again and affect your liver. Tell your prescriber if you notice any signs of liver problems, like nausea, stomach pain, clay-colored stools, or yellowing of your skin or whites of your eyes.
                    Does Amjevita (adalimumab-atto) need to be refrigerated?
                    Yes, Amjevita (adalimumab-atto) should be stored in the refrigerator. But you can keep it at room temperature for up to 14 days if needed. Just make sure to protect the medication from light by keeping it in the original container. Write the date you took Amjevita (adalimumab-atto) out of the refrigerator, and throw it away after 14 days have passed.
                    GoodRxEducationalIcon

                    How to save using GoodRx

                    Compare Prices
                    1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
                    Select your free coupon
                    2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
                    Show coupon to your pharmacist
                    3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
                    Get free couponLearn more
                    warings-icon

                    What are the risks and warnings for Amjevita (adalimumab-atto)?

                    Amjevita (adalimumab-atto) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                    risk-warning

                    Serious infections

                    • Risk factors: Taking other medications that weaken the immune system | Age 65 years or older | Active, long-term, or an infection that keeps coming back | Traveling to high risk areas | Having other conditions that raise the risk of infection

                      Amjevita (adalimumab-atto) can raise your risk of serious or life-threatening infections. Your risk might be higher if you're 65 years or older, taking other medications that can weaken the immune system (e.g., methotrexate, Orencia (abatacept), Kineret (anakinra), corticosteroids), or have other health conditions. Discuss your medical history with your prescriber before starting Amjevita (adalimumab-atto), especially if you've had tuberculosis or hepatitis B. They will review your risk before prescribing the medication. If you develop an infection while taking Amjevita (adalimumab-atto), you might have to stop the medication in order to give your immune system a chance to fight the infection.

                      risk-warning

                      Cancers

                      • Risk factors: Taking other medications that weaken the immune system | History of cancer | People with chronic obstructive pulmonary disease (COPD) with a history of smoking

                        In clinical studies, more people developed cancer while taking a medication similar to Amjevita (adalimumab-atto) compared to those who weren't taking it. The most common types of cancer reported were lymphoma, leukemia, and skin cancers. Your prescriber will assess your risk before starting treatment and monitor you while you're taking the medication. If you notice any unusual symptoms, be sure to contact your prescriber.

                        risk-warning

                        Severe allergic reactions

                        Although rare, Amjevita (adalimumab-atto) can cause severe allergic reactions, including anaphylaxis, which can be life-threatening. If you notice symptoms like a rash, itching, trouble breathing, or swelling in your face or throat, stop the medication and get medical help right away.

                        risk-warning

                        Nervous system effects

                        • Risk factors: History of nerve problems

                          TNF blockers like Amjevita (adalimumab-atto) have been linked to rare cases of new or worsening nerve problems, including multiple sclerosis (MS) and Guillain-Barré syndrome. Let your prescriber know if you already have or recently developed a nerve condition. They will help to review the risks and benefits of taking this medication. If you notice numbness or tingling, weakness in your arms or legs, vision problems, or dizziness, contact your care team.

                          risk-warning

                          Low blood cell counts

                          There have been reports of people having low blood cells while taking Amjevita (adalimumab-atto). This can affect your body's ability to fight infections and raise your risk for bleeding. Contact your prescriber if you develop a fever that doesn't go away, easy bruising, pale skin, or bleeding.

                          risk-warning

                          Heart failure

                          People taking medications like Amjevita (adalimumab-atto) have had new or worsening cases of heart failure. Speak with your prescriber if you currently have heart failure. They'll help you decide if Amjevita (adalimumab-atto) is right for you. Also let them know if you start to have shortness of breath, swelling in the legs, ankles, or feet, irregular heartbeat, or tiredness or weakness, as these can be signs of heart failure.

                          risk-warning

                          Lupus-like syndrome

                          Amjevita (adalimumab-atto) can rarely cause a condition called lupus-like syndrome. Contact your prescriber if you experience a rash, easy bruising or bleeding, or feel more tired than usual.

                          dosage

                          Amjevita (adalimumab-atto) dosage forms

                          Typical dosing for Amjevita (adalimumab-atto)

                          Adults

                          • Rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: The typical starting dose is 40 mg injected under the skin every other week.

                          • Crohn's disease and ulcerative colitis: The typical dose is 160 mg injected under the skin on Day 1, followed by 80 mg on Day 15, then 40 mg every other week starting Day 29 (2 weeks later).

                          • Plaque psoriasis and uveitis: The typical dose is 80 mg injected under the skin on Day 1, followed by 40 mg every other week starting 1 week after the first dose.

                          • Hidradenitis suppurativa: The typical dose is 160 mg injected under the skin on Day 1, followed by 80 mg on Day 15, then 40 mg every week OR 80 mg every other week starting Day 29.

                          Children

                          • Juvenile idiopathic arthritis and Crohn's disease: The dose will be based on your child's body weight. Typically it will be injected under the skin once every other week.

                          interactions

                          Interactions between Amjevita (adalimumab-atto) and other drugs

                          Amjevita (adalimumab-atto) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Amjevita (adalimumab-atto). Please note that only the generic name of each medication is listed below.

                          Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                          drug-cost

                          How much does Amjevita (adalimumab-atto) cost?

                          To access savings, use a GoodRx coupon and pay just a fraction of the retail price.View prices & coupons
                          alternatives

                          What are alternatives to Amjevita (adalimumab-atto)?

                          There are a number of medications that your doctor can prescribe in place of Amjevita (adalimumab-atto). Compare a few possible alternatives below.
                          Amjevita (adalimumab-atto)
                          Used for:
                          $1370.45 Lowest GoodRx priceView Prices
                          Used for:
                          • Rheumatoid arthritis (RA)

                          • Plaque psoriasis (PsO) and psoriatic arthritis (PsA)

                          • Ankylosing spondylitis (AS)

                          • Childhood arthritis (polyarticular juvenile idiopathic arthritis, JIA)

                          $8034.48 Lowest GoodRx priceView Prices
                          Used for:
                          • Rheumatoid arthritis (RA) - adults only

                          • Juvenile idiopathic arthritis (JIA) - people age 2 and older

                          • Psoriatic arthritis (PsA) - adults only

                          • Ankylosing spondylitis (AS) - adults only

                          • Crohn's disease (CD) - people age 6 and older

                          • Ulcerative colitis (UC) - people age 5 and older

                          • Plaque psoriasis - adults only

                          • Hidradenitis suppurativa (HS) - people age 12 and older

                          • Uveitis - people age 2 and older

                          $1115.35 Lowest GoodRx priceView Prices
                          latest news

                          What is the latest news about Amjevita (adalimumab-atto)?

                          images

                          Amjevita (adalimumab-atto) images

                          yellow - AMJEVITA SureClick 40mg / 0.4mL Autoinjector Solution for Injection
                          This medicine is Yellow Carton.yellow - AMJEVITA SureClick 40mg / 0.4mL Autoinjector Solution for Injection

                          Get savings updates for Amjevita (adalimumab-atto)

                          Receive price alerts, news, and other messages from GoodRx about Amjevita (adalimumab-atto) and other healthcare topics and relevant savings offers.

                          By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.

                          References

                          Best studies we found
                          View All References (4)

                          LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. (2017). Adalimumab. National Institute of Diabetes and Digestive and Kidney Diseases.

                          Markus, R., et al. (2019). A review of the totality of evidence supporting the development of the first adalimumab biosimilar ABP 501. Advances in Therapy.

                          National Eye Institute. (2024). Uveitis.

                          Solhjoo, M., et al. (2023). Drug-induced lupus erythematosus. StatPearls.

                          GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
                          Was this page helpful?

                          Browse medications

                          View All

                          Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.