The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low blood sugar (up to 67%)
- Cough (up to 29%)
- Throat pain or irritation (up to 6%)
- Headache (up to 5%)
Less Common Side Effects
- Diarrhea
- Nausea
- Feeling tired
- Weight gain
- Bronchitis
- Urinary tract infection
Afrezza serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Bronchospasm: trouble breathing, tightness in the chest, wheezing, cough, tiredness, dizziness
- Severely low blood sugar: dizziness, shakiness, feeling confused, feeling irritable or anxious, feeling faint, sweating, extreme hunger, can't think clearly
- Ketoacidosis (high ketone levels in the blood): nausea, vomiting, stomach pain, thirsty, dry mouth, fruity breath, trouble breathing, deep and fast breaths, confusion
- Very low potassium levels: weakness, dizziness, muscle cramps or twitches, constipation, irregular heartbeat
- Severe allergic reactions: rash; hives; swelling of face, tongue, or throat; trouble breathing
When do Afrezza possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Y
Risk of low blood sugar
Cough
Throat pain or irritation
Decreased lung function
Source: DailyMed
The following Afrezza side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Diabetic ketoacidosis (DKA)—increased thirst or amount of urine, dry mouth, fatigue, fruity odor to breath, trouble breathing, stomach pain, nausea, vomiting
- Low blood sugar (hypoglycemia)—tremors or shaking, anxiety, sweating, cold or clammy skin, confusion, dizziness, rapid heartbeat
- Low potassium level—muscle pain or cramps, unusual weakness or fatigue, fast or irregular heartbeat, constipation
- Wheezing or trouble breathing that is worse after use
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):









