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Humalog 50/50

Humalog 50/50 Side Effects

Allison Gourley, PharmDMichelle Nguyen, PharmD
Reviewed by Allison Gourley, PharmD, Michelle Nguyen, PharmD
Last reviewed on December 2, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low blood sugar
  • Injection site reaction (e.g., redness, swelling, itching)
  • Changes in skin shape at the site of the injection
  • Weight gain
  • Swelling in the hands and feet
  • Itching
  • Rash

Humalog 50/50 serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe hypoglycemia (dangerously low blood sugar): if not treated, severe hypoglycemia can lead to unconsciousness, seizures, and even death
  • Severe allergic reactions: rash, hives, swelling of face, tongue, and throat, difficulty breathing
  • Dangerously low levels of potassium: if not treated, it can lead to difficulty breathing, irregular heartbeat, and even death

Source: DailyMed

The following Humalog 50/50 side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Anxiety

blurred vision

chills

cold sweats

confusion

cool, pale skin

cough

decreased urine

depression

difficulty with swallowing

dizziness

dry mouth

fast heartbeat

flushing or redness of the skin

headache

hives, itching, skin rash

increased hunger

increased thirst

irregular heartbeat

loss of appetite

muscle pain or cramps

nausea

nervousness

nightmares

numbness or tingling in the hands, feet, or lips

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

seizures

shakiness

slurred speech

sweating

swelling of the arms or legs

tightness in the chest

unusual tiredness or weakness

unusually warm skin

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

redistribution or accumulation of body fat

weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.
Michelle Nguyen, PharmD, has been a clinical pharmacist for 6 years (and counting). She has a diverse skill set within managed care pharmacy, specifically in the settings of a medical group, pharmacy benefit manager (PBM), and health plan.

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