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Humalog

Humalog Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on October 27, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Type 1 diabetes:

  • Flu-like symptoms (35%)
  • Sore throat (33%)
  • Runny nose (25%)
  • Headache (30%)
  • Pain (20%)
  • Cough (17%)
  • Infection (14%)

Type 2 diabetes:

  • Headache (12%)
  • Pain (11%)
  • Infection (10%)

Less Common Side Effects

  • Weight gain
  • Swelling
  • Reactions at the injection site (e.g., redness, swelling, itching)

Humalog serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severely low blood sugar: dizziness, shakiness, feeling confused, feeling irritable or anxious, feeling faint, sweating, extreme hunger, not able to think clearly
  • Ketoacidosis (high ketone levels in the blood): nausea, vomiting, stomach pain, tiredness, thirsty, dry mouth, fruity breath, trouble breathing
  • Severely low potassium levels: weakness, muscle cramps or twitches, constipation, abnormal heartbeat, tiredness, trouble breathing
  • Severe allergic reactions: rash; hives; swelling of face, tongue, and throat; trouble breathing

Source: DailyMed

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The following Humalog side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Anxious or nervous feeling

behavior change similar to being drunk

blurred vision

chills

cold sweats

confusion or difficulty thinking

depression

dizziness or lightheadedness

drowsiness

excessive hunger

fast heartbeat

fever

headache

irritability or abnormal behavior

lower back or side pain

nightmares

painful or difficult urination

restless sleep

seizures

shakiness

slurred speech

tingling in the hands, feet, lips, or tongue

Less common

Dry, red, hot, or irritated skin

Rare

Depression of the skin at the injection site

dryness of the mouth

fast or weak pulse

itching, redness, or swelling at the injection site

muscle cramps or pain

nausea

skin rash or itching over the whole body

sweating

thickening of the skin at the injection site

trouble breathing

unusual tiredness or weakness

vomiting

Incidence not known

Bloating or swelling of the face, arms, hands, lower legs, or feet

decreased urine

difficulty with swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fast, pounding, or irregular heartbeat or pulse

hives or itching skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

redistribution or accumulation of body fat

tightness in the chest

unusual weight gain or loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Body aches or pain

congestion

runny nose

sneezing

sore throat

stuffy nose

tender, swollen glands in the neck

unusual tiredness or weakness

voice changes

Incidence not known

Redness, swelling, or itching at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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