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Xofluza Coupon - Xofluza 1 tablet of 40mg dose pack

Xofluza

baloxavir marboxil
Used for Flu
Used for Flu

Xofluza (baloxavir marboxil) is an antiviral medication. It's used to treat and sometimes prevent the flu with a single dose. It's taken within 48 hours at the start of flu symptoms or exposure to someone who has the flu. Xofluza (baloxavir marboxil) comes as tablets and a liquid for people ages 5 years and older. Common side effects include sinusitis, diarrhea, and nausea. There's currently no generic version of this medication available.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Cydnee Ng, PharmD
Last reviewed on May 27, 2025
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostAlternativesLatest newsImagesPricesMedicare
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What is Xofluza (baloxavir marboxil)?

What is Xofluza (baloxavir marboxil) used for?

  • Flu treatment for people 5 years and older with flu symptoms for no more than 48 hours

  • Flu prevention for people 5 years and older who've been in contact with someone who has the flu

How Xofluza (baloxavir marboxil) works

Xofluza (baloxavir marboxil) is an antiviral medication. It fights the flu by stopping the influenza virus from making copies of itself. This helps stop the infection from spreading in your body.

When does Xofluza (baloxavir marboxil) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsXofluza
Drug ClassAntiviral
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only

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What are the side effects of Xofluza (baloxavir marboxil)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Adults and adolescents:
  • Diarrhea (3%)
  • Bronchitis (3%)
  • Nausea (2%)
  • Sinusitis (swelling in the sinuses, 2%)
Children 5 to 11 years old:
  • Diarrhea (5%)
  • Vomiting (5%)

Other Side Effects

  • Headache

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Serious allergic reaction: hives; trouble breathing; swelling of your lips, throat, tongue, or face

Source: DailyMed

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The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

pros-and-cons

Pros and cons of Xofluza (baloxavir marboxil)

thumbs-up

Pros

Can help treat and prevent flu infection

Can help you feel better from the flu in about 2 days

Generally well-tolerated with few side effects

thumbs-down

Cons

Must take within 48 hours of the start of flu symptoms or exposure

Not approved for children younger than 5 years old

Not the preferred treatment for people who are pregnant

pharmacist-tips

Pharmacist tips for Xofluza (baloxavir marboxil)

pharmacist

  • Xofluza (baloxavir marboxil) only works to treat the influenza virus. It doesn't work for any other infection, like bacterial or other viral ones (e.g., COVID-19, common cold). Sometimes, it can be hard to tell if you have the flu because symptoms can be a lot like other infections. Ask a healthcare professional if you're not sure if you have the flu and the best options for you.

    • Once you get Xofluza (baloxavir marboxil) from the pharmacy, take it as soon as you can after your symptoms start or after being around someone with the flu. It can take a few days for you to start feeling better after you take it. So the sooner you take it, the sooner you'll start to feel better.

      • You can take Xofluza (baloxavir marboxil) with or without food. If you're taking it with food, avoid things that are high in calcium (e.g., milk, yogurt, cheese, fortified drinks). These foods and beverages can make the medication work less well.

        • For the liquid version of Xofluza (baloxavir marboxil): Take the medication within 10 hours after the pharmacy prepares it for you. If you're not taking it right away, keep it at room temperature. Use only the oral syringe the pharmacy gives you to measure the dose. After you take your dose, throw away any leftover medication in the bottle.

          • You might need to take Xofluza (baloxavir marboxil) a few hours after taking certain medications. This includes antacids and supplements with calcium, iron, magnesium, selenium, or zinc. Taking them at the same time can make Xofluza (baloxavir marboxil) not work as well.

            • If your symptoms don't get better or get worse after taking Xofluza (baloxavir marboxil), talk to your prescriber. You might have a different infection or need a different treatment.

              • Xofluza (baloxavir marboxil) doesn't replace the annual flu shot. This medication helps you feel better sooner, but the flu can still be dangerous. It's especially risky for young children, older adults, and people with long-term health conditions. The best way to protect yourself is getting your flu shot each year by the end of October.

                • Wait at least 17 days after taking Xofluza (baloxavir marboxil) before getting the nasal spray flu vaccine. Xofluza (baloxavir marboxil) might make this type of flu vaccine not work as well.

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                  faqs

                  Frequently asked questions about Xofluza (baloxavir marboxil)

                  What happens if you take Xofluza (baloxavir marboxil) after 48 hours from when your symptoms start or when you get in contact with someone with the flu?
                  It's not clear how well Xofluza (baloxavir marboxil) works if you take it after the 48-hour window. That's because the medication wasn't studied in this situation. Xofluza (baloxavir marboxil) works best when taken early, within the first 2 days of your symptoms or of being around someone with the flu. Taking it later might not help you feel better faster or stop the flu from spreading. If you miss the 48-hour window, ask your prescriber about your options.
                  How long does Xofluza (baloxavir marboxil) stay in your system?
                  It takes a little over 2 weeks for Xofluza (baloxavir marboxil) to fully leave your system. This is based on the medication's half-life, which measures how long it takes your body to get rid of half the medication.
                  What's the difference between Xofluza and Tamiflu?
                  Xofluza (baloxavir marboxil) and oseltamivir (Tamiflu) are both antivirals that help treat and prevent the flu. But they work in different ways. Another difference is how many days you need to take the medication. You only need to take Xofluza one time to treat or prevent the flu. But for Tamiflu, you need to take it every day for 5 days to treat the flu and usually for 10 days to prevent it. Also, Tamiflu is approved for children in a younger age group than Xofluza. Ask a healthcare professional to help you compare between the two medications.
                  Can you take Tamiflu and Xofluza together?
                  Your prescriber will probably tell you to just take one of the two medications. We don't know if it's safe to take oseltamivir (Tamiflu) and Xofluza (baloxavir marboxil) together. It's also not clear if taking both helps more for the flu than taking just one. Early studies show that taking both might not help too much more for severe flu that needs hospital care.
                  How long does it take Xofluza (baloxavir marboxil) to work?
                  Xofluza (baloxavir marboxil) gets absorbed into your body and starts working to fight the flu within 4 hours. In studies, most adults and teens had no or mild flu symptoms about 1 to 2 days after taking Xofluza (baloxavir marboxil). For children ages 5 to 11, it took longer to be free of flu symptoms — about 5 days after taking the medication. Xofluza (baloxavir marboxil) works best when you take it within 48 hours of the start of your flu symptoms or being around someone with the flu. If you don't feel better after a couple days, talk to a healthcare professional. They can check what's going on.
                  How long are you contagious after taking Xofluza (baloxavir marboxil)?
                  Studies show that only about 7% of people still had infectious flu virus in their body 5 days after taking Xofluza (baloxavir marboxil). This means most people aren't likely to spread the flu to others 5 days after taking the medication. Without any treatment, people are usually contagious for up to 7 days after getting sick.
                  Can Xofluza (baloxavir marboxil) be crushed?
                  It's not recommended to crush Xofluza (baloxavir marboxil) tablets. There isn't enough information to know how well the tablets work if they're crushed. If you have trouble swallowing pills whole, tell your prescriber. They can prescribe the liquid version of Xofluza (baloxavir marboxil) for you.
                  Is Xofluza (baloxavir marboxil) over the counter?
                  No, Xofluza (baloxavir marboxil) isn't over the counter. You need a prescription for it from a healthcare professional.
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                  What are the risks and warnings for Xofluza (baloxavir marboxil)?

                  Xofluza (baloxavir marboxil) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Allergic reaction

                  Serious allergic reactions to Xofluza (baloxavir marboxil) are possible. Sometimes, they can be life-threatening. These reactions can include hives and anaphylaxis (closing of the throat and trouble breathing). They can also look like swelling of the face, lips, or tongue. Call for emergency help right away if this happens.

                  risk-warning

                  Risk of bacterial infections

                  Xofluza (baloxavir marboxil) is an antiviral medication. It only works against the flu virus, not bacterial infections. Some bacterial infections can start with flu-like symptoms or show up while you still have the flu.

                  Tell your care team right away if you feel sick again, get a new fever or chills, or start feeling worse. These could be signs of a new or different infection that needs other treatment.

                  dosage

                  Xofluza (baloxavir marboxil) dosage forms

                  The average cost for 1 dose pack of 1 tablet of 40mg of Xofluza (baloxavir marboxil) is $164.74 with a free GoodRx coupon. This is 24.62% off the average retail price of $218.54.
                  dose pack
                  Dose pack
                  DosageQuantityPrice as low asPrice per unit
                  2 tablets of 20mg1 dose pack$180.00$180.00
                  1 tablet of 40mg1 dose pack$164.74$164.74
                  2 tablets of 40mg1 dose pack$197.37$197.37
                  1 tablet of 80mg1 dose pack$169.33$169.33

                  Typical dosing for Xofluza (baloxavir marboxil)

                  The dose is based on your body weight.

                  • Weigh 176 lbs (80 kg) or more: The typical dose is 80 mg by mouth one time only.

                  • Weigh 44 lbs to 175 lbs (20 kg to 79.9 kg): The typical dose is 40 mg by mouth one time only.

                  • Weigh less than 44 lbs (20 kg): The typical dose is 2 mg/kg by mouth one time only. Only use the liquid form of the medication.

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                  alternatives

                  What are alternatives to Xofluza (baloxavir marboxil)?

                  There are a number of medications that your doctor can prescribe in place of Xofluza (baloxavir marboxil). Compare a few possible alternatives below.
                  Xofluza (baloxavir marboxil)
                  Used for:

                  • Flu treatment for people 5 years and older with flu symptoms for no more than 48 hours

                  • Flu prevention for people 5 years and older who've been in contact with someone who has the flu

                  $164.74 Lowest GoodRx priceView Prices
                  Tamiflu (oseltamivir)
                  Used for:

                  • Flu treatment (flu types A and B) in people 2 weeks of age and older

                  • Flu prevention (flu types A and B) in people 1 year of age and older

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                  Relenza (zanamivir)
                  Used for:

                  • Flu treatment (flu types A and B) - age 7 years and older

                  • Flu prevention (flu types A and B) - age 5 years and older

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                  What is the latest news about Xofluza (baloxavir marboxil)?

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                  Xofluza (baloxavir marboxil) images

                  Yellow Oblong Bxm40 - Xofluza 40mg Tablet
                  This medicine is Yellow, Oblong Dose Pack Imprinted With "Bxm40".Yellow Oblong Bxm40 - Xofluza 40mg Tablet

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