Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Tamiflu (oseltamivir) and Rapivab (peramivir) are both antiviral medications used to treat the flu, but they have some key differences. Tamiflu is taken orally, either as a capsule or a liquid, and must be started within 48 hours of flu symptoms. It can also be used to prevent the flu if you've been exposed. Rapivab, on the other hand, is given as a single infusion through a vein by a healthcare professional and is only used for treatment, not prevention. Rapivab must also be started within 48 hours of flu symptoms. Tamiflu is available in a lower-cost generic form, while Rapivab does not have a generic version and can be expensive. Tamiflu can be used in children as young as 2 weeks old and pregnant women, whereas Rapivab is typically used for people who can't take other antiviral medications and is approved for use in children 6 months and older. Both medications can cause serious allergic reactions and unusual behaviors, especially in children, but Rapivab is more likely to be used in a hospital or emergency room setting.
Tamiflu (oseltamivir)
Rapivab (peramivir)
Tamiflu (oseltamivir)
Rapivab (peramivir)
Summary of Tamiflu vs. Rapivab
Summary for Antiviral
Prescription only
Tamiflu (oseltamivir) works well to treat the flu, but you have to take your first dose within 48 hours of the start of your flu symptoms. It can also help prevent the flu if you've recently been in close contact with someone who has the flu. Kids as young as 2 weeks old can take Tamiflu (oseltamivir), but keep in mind that the pediatric dosing is different than adult dosing. It's only available with a prescription (not available over the counter), so don't wait to see your provider if you start feeling sick. This medication comes as a brand or generic capsule or fruit-flavored liquid. Tamiflu (oseltamivir) can cause side effects like nausea and vomiting.
Summary for Antiviral
Prescription only
Rapivab (peramivir) is an antiviral medication that's used to treat the flu in people 6 months and older. It's given as a one-time intravenous (IV) infusion by a trained healthcare professional, typically in a hospital setting. It should only be used within 2 days of when symptoms started. Diarrhea is the most common side effect of this medication.
Indications of Tamiflu vs. Rapivab
Indications for
•Flu treatment (flu types A and B) in people 2 weeks of age and older
•Flu prevention (flu types A and B) in people 1 year of age and older
•Requires a prescription from your healthcare provider
•Only works if you take it within 2 days (48 hours) from when you first felt flu symptoms to treat (or when you were first in contact with someone who has the flu to prevent)
Pros and Const for Antiviral
Pros
•Single dose
•Can shorten the amount of time you have flu symptoms by 1 day