The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Vomiting (up to 93%)
- Diarrhea (up to 92%)
- Nausea (up to 86%)
- Higher liver labs, suggesting liver irritation (up to 81%)
- Vision changes (up to 71%)
- Runny nose, sore throat, and other symptoms of an upper respiratory infection (up to 64%)
- Headache (up to 58%)
- Muscle pain (up to 58%)
- Fever (up to 50%)
- Swelling in the legs and feet (up to 49%)
- Lower blood cell counts (up to 48%)
- Mouth sores (up to 46%)
- Tiredness (up to 46%)
- Constipation (up to 43%)
- Lower appetite (up to 42%)
- Itching (up to 35%)
- Stomach pain (up to 26%)
Please note: The side effects you experience can differ depending on factors, such as your age, what type of cancer you’re being treated for, and whether you’re taking any other anticancer medications.
Less Common Side Effects
- Dizziness
- Heartburn
- Numbness in fingers and toes
Xalkori serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious lung problems: sudden cough, fever, and difficulty breathing.
- Heart rhythm problems: lightheadedness, blurry vision, fainting, seizures, loss of consciousness
- Serious liver problems: nausea, vomiting, tiredness, stomach pain or swelling, pale-colored stool, dark-colored urine, yellowing of the whites of the eyes or skin
Source: DailyMed
The following Xalkori side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Black, tarry stools
bloating or swelling of the face, arms, hands, lower legs, or feet
blurred or loss of vision
body aches or pain
chest pain, discomfort, or tightness
chills
colicky or burning stomach pain
difficult or labored breathing
difficulty in swallowing
disturbed color perception
double vision
ear congestion
halos around lights
headache
hoarseness
increased sensitivity to pain or touch
irregular heartbeat
lightheadedness, dizziness, or fainting
loss of appetite
loss of voice
lower back or side pain
nerve pain
night blindness
overbright appearance of lights
pain in the back of throat or chest when swallowing
pain or burning in the throat
painful or difficult urination
pale skin
rapid weight gain
recurrent fainting
runny or stuffy nose
seeing flashes or sparks of light
slow or irregular heartbeat
sores, ulcers, or white spots on the lips or tongue or inside the mouth
swelling
trouble breathing
tunnel vision
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight gain or loss
vomiting
vomiting blood or material that looks like coffee grounds
weakness in the arms, hands, legs, or feet
Less common
blue lips, fingernails, or skin
clay-colored stools
confusion
dark urine
fast heartbeat
flushed, dry skin
fruit-like breath odor
increased hunger
increased thirst
increased urination
irregular, fast or slow, or shallow breathing
itching, skin rash
loss of consciousness
stomach pain or tenderness
sweating
swelling of the feet or lower legs
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Acid or sour stomach
back pain
belching
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
change in taste
increased weight
indigestion
loss of taste
muscle spasm or weakness
pain in the arms or legs
stomach discomfort or upset
trouble in walking
unsteadiness or awkwardness
weakness in the arms, hands, legs, or feet
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
