Key takeaways:
Soy foods have many nutritional benefits. But some have raised concerns about the possibility of estrogen-like effects on the body.
The latest reviews of studies show that soy is safe in humans and can help reduce the risk of certain kinds of cancer, especially breast and prostate cancer.
You can enjoy foods with soy as part of a nutritious and well-balanced diet.
Few foods have been as polarizing as soy. In the past few decades, some have praised soy as a healthy, nutritious food that can lower cholesterol and help with weight loss. At the same time, others have raised concerns about the possible estrogen-like effects of soy, which could lead to fertility problems or even increase your chance of cancer. So, is soy good or bad for you?
A comprehensive review of the evidence sheds light on this question. Researchers reviewed 417 reports based on human data and concluded that soy has no negative effects on thyroid health, estrogen levels, or fertility. And in some areas, scientists found soy to be beneficial.
Soy foods are made from soybeans, which are a type of legume native to East Asia. They’re named this way because they grow in pods containing seeds or beans. Most soy products are innovations from cuisines across Asia.
Discover a simple way to manage diabetes
Patients can use GoodRx to save up to 40% on OneTouch Ultra Strips.
Common nonfermented soy products include:
Fresh soybeans (edamame)
Fresh tofu
Soy milk
Soybean sprouts
Soybean oil, a very common ingredient in processed foods
Soy lecithin, a common emulsifier used to mix oil and water (used in everything from chocolate to baked goods to dietary supplements)
Common fermented soy products include:
Soy sauce
Miso
Soy pastes
Tempeh
Milk alternatives: Curious about a plant-based milk alternative? An expert helps you pick the best option for you.
Plant proteins: Whether or not you’re a vegetarian, plant-based proteins are healthy parts of a nutritious diet. Check out these tasty and protein-packed options.
Miso and your health: Miso is a fermented soybean that you can use in many different recipes. Learn about its health benefits and get ideas on working it into your diet.
Some people think that soy is bad for you because soybeans contain a high concentration of isoflavones. These are compounds that have a similar structure to estrogen. They are considered “phytoestrogens,” or plant-derived estrogens. Some people worry that because of this, eating soy will cause hormonal changes in the body.
Concerns about soy have been mostly theoretical. For example, people worry that if phytoestrogen can act like estrogen, it might have feminizing effects on men or disrupt fertility. Other concerns — like increased risk of breast cancer, thyroid problems, and fertility — have been based on animal studies. But animals and humans metabolize isoflavones very differently.
In 2016, the European Food Safety Authority reviewed over 25 years of data in humans and concluded that soy is safe and sometimes beneficial. There’s no evidence that soy is bad for you, and there’s emerging evidence that it may help prevent or treat certain chronic conditions.
Processed foods in general have a reputation for being bad for your health. This is for good reason — processed foods usually have more fat, salt, and simple sugars than unprocessed foods. Processed foods also provide less nutrients. Take a potato chip versus a baked potato. They’re both made from potatoes, but one is much more healthful than the other. Soy is no different.
Soy products that are unprocessed or minimally processed provide all the nutritional benefits that soy has to offer — without the unwanted additives. Examples of these products are edamame, tofu, soy milk, and tempeh. Highly processed soy products, on the other hand, often get stripped of their vitamins, minerals, and fiber, while fats and salt are added for flavor. Examples of processed soy products are soy proteins (used in things like protein bars and protein powders) and soy-based meat substitutes.
No. Soy contains isoflavones, chemicals that look like estrogen on a molecular level. Because of the similarity between isoflavones and estrogen, people have worried that eating lots of soy could be similar to having higher estrogen levels in your body. Research has shown that this isn’t the case.
Even though isoflavones can interact with estrogen receptors in the body, this interaction tends to be weak and doesn’t seem to have harmful effects. Given the possibility of mimicking estrogen, there have also been worries that too much soy could lead to infertility in women. Studies have found that a diet high in soy can prolong the menstrual cycle by a day, but it doesn’t affect fertility.
People have also worried about soy’s effect on men. Since isoflavones look like estrogen, it has been thought that men who eat lots of soy could become infertile or develop female characteristics, such as breasts. While some early studies showed that a high intake of soy was associated with lower sperm counts, more recent research has shown that this is not the case.
The most current evidence suggests that there’s no association between soy intake and sperm counts or fertility problems. Despite the controversies, the truth is that soy hasn’t been found to have any effects on testosterone or estrogen levels in men.
No. In the past, some raised concerns after studies with rodents showed that giving them high amounts of isolated isoflavones led to a goiter and altered their thyroid function. But this was probably related to the high amount of isoflavones administered, and more importantly, the different ways in which rodents and humans metabolize soy products.
More recent reviews of over 14 different studies showed that soyfoods didn’t affect thyroid function.
Of the different kinds of legumes, soybeans are the only ones considered a “complete protein.” That means they contain all nine essential amino acids that the body cannot make. Soybeans are an excellent source of protein and unsaturated fat, and vitamins and minerals such as:
Iron
Calcium
Potassium
B vitamins
Let’s take a closer look at some of the possible health benefits of soy.
Eating soy food may help you lose weight when part of a nutritious diet. People often use soy as a replacement for animal protein, which usually has more calories. As part of a well-balanced diet, soy can be a good source of protein, fiber, and healthy vitamins and minerals.
A small study showed that people who used soy-based protein as part of a high-protein, weight-loss diet and those who ate animal protein lost the same amount of weight. In other words, soy may be just as effective as animal protein in helping with a healthy and balanced weight loss.
Another study found that people with polycystic ovarian syndrome (PCOS) who maintained a high-protein diet lost more weight when half their protein was from soy compared with those who had a high-protein diet just from animal protein.
As part of a low-calorie diet, people doing a meal-replacement diet seemed to lose more weight with soy meal replacements than milk-based ones.
Studies have shown that eating soy can actually help protect against some forms of cancer, like breast cancer and prostate cancer. Multiple studies have shown that children and adolescents who consume more soy have lower breast cancer rates in adulthood. A large meta-analysis also showed that women who had higher soy intake had higher survival rates after being diagnosed with breast cancer. And a study looking at the link between soy and prostate cancer found that high soy consumption seemed to lower the risk of prostate cancer by as much as 50%.
Soy also seems to play a role in stomach cancer, but the picture is a bit more complicated here. Multiple studies have found that fresh and unprocessed soy products can reduce the risk of stomach cancer, but highly processed or fermented soy products can actually increase your risk of it. Nobody knows why this might be the case, but some people think that the high salt content of some processed soy products can explain why they’re associated with higher rates of stomach cancer.
In 2000, the American Heart Association recommended soy as a way to help lower cholesterol. But 8 years later, they retracted that recommendation due to inconsistent and conflicting studies.
Part of the problem may be that some people with high soy intake eat higher amounts of processed soy — and processed foods are worse for heart health. More recent studies seem to suggest that soy intake can lower low-density lipoprotein (LDL), or “bad,” cholesterol by a small but notable amount.
A review of research in 2019 looked at 46 different studies and found that eating about 25 g per day of soy lowered LDL by about 3% to 4% after 6 weeks. Soy also seems to have a beneficial effect on heart health overall. Eating one serving per week of tofu has been linked to an 18% lower risk of heart disease compared to those who never ate tofu.
No, soy milk doesn’t have estrogen. Like other types of soy, soy milk contains phytoestrogens, which can behave like estrogen in the body. But they’re not the same.
The amount of phytoestrogens in soy milk can be affected by exactly how the soybeans are processed to make soy milk (for example, soaking the soybeans in water leads to more phytoestrogens in the soy milk). But no matter how the soy milk is made, it will not contain estrogen.
No, soy is not bad for women. As discussed above, it may protect against breast cancer and be helpful for women with PCOS. But it may have more benefits for women beyond this, particularly after menopause. The beneficial compounds in soy may help slow bone loss, improve muscle function, and help women with weight loss after menopause.
There’s quality research that debunks many of the myths surrounding soy and its alleged harmful effects. Not only is it safe, it may also have potential health benefits. For example, soy may lower cholesterol levels, and it appears to be beneficial in preventing or treating certain kinds of cancer. So you can enjoy one of the most nutritious forms of plant-based protein without worry.
American Heart Association. (2020). Soy-rich foods like tofu may help lower heart disease risk.
Anderson, J. W., et al. (2005). Weight loss and lipid changes with low-energy diets: Comparator study of milk-based versus soy-based liquid meal replacement interventions. Journal of the American College of Nutrition.
Baranska, A., et al. (20220. The role of soy isoflavones in the prevention of bone loss in postmenopausal women: A systematic review with meta-analysis of randomized controlled trials. Journal of Clinical Medicine.
Blanco Mejia, S., et al. (2019). A meta-analysis of 46 studies identified by the FDA demonstrates that soy protein decreases circulating LDL and total cholesterol concentrations in adults. Journal of Nutrition.
Chang, H. C., et al. (2000). Dietary genistein inactivates rat thyroid peroxidase in vivo without an apparent hypothyroid effect. Toxicology and Applied Pharmacology.
Chavarro, J. E., et al. (2008). Soy food and isoflavone intake in relation to semen quality parameters among men from an infertility clinic. Human Reproduction.
Chi, F., et al. (2013). Post-diagnosis soy food intake and breast cancer survival: A meta-analysis of cohort studies. Asian Pacific Journal of Cancer Prevention.
Erdman, J. W., Jr., et al. (2000). Soy protein and cardiovascular disease: A statement for healthcare professionals from the Nutrition Committee of the AHA. Circulation.
Higdon, J. (2016). Soy isoflavones. Linus Pauling Institute Oregon State University.
Jargin, S. V. (2014). Soy and phytoestrogens: Possible side effects. German Medical Science.
Karamali, M., et al. (2018). The effect of dietary soy intake on weight loss, glycaemic control, lipid profiles and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome: A randomised clinical trial. Journal of Human Nutrition and Dietetics.
Lee, S. A., et al. (2009). Adolescent and adult soy food intake and breast cancer risk: Results from the Shanghai Women's Health Study. American Journal of Clinical Nutrition.
Lu, D., et al. (2017). Meta-analysis of soy consumption and gastrointestinal cancer risk. Scientific Reports.
Messina, M. (2016). Soy and health update: Evaluation of the clinical and epidemiologic literature. Nutrients.
Messina, M., et al. (2006). Effects of soy protein and soybean isoflavones on thyroid function in healthy adults and hypothyroid patients: A review of the relevant literature. Thyroid.
Messina, M., et al. (2021). Neither soyfoods nor isoflavones warrant classification as endocrine disruptors: A technical review of the observational and clinical data. Critical Reviews in Food Science and Nutrition.
Munro, I. C., et al. (2003). Soy isoflavones: A safety review. Nutrition Reviews.
Neacsu, M., et al. (2014). Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: A randomized crossover trial. American Journal of Clinical Nutrition.
Niyibituronsa, M., et al. (2018). The effect of different processing methods on nutrient and isoflavone content of soymilk obtained from six varieties of soybean grown in Rwanda. Food Science & Nutrition.
NutritionValue.org. (n.d.). Soybeans, raw, mature seeds.
Reed, K., et al. (2021) Neither soy nor isoflavone intake affects male reproductive hormones: An expanded and updated meta-analysis of clinical studies. Reproductive Toxicology.
Rizzo, G., et al. (2022). The role of soy and soy isoflavones on women's fertility and related outcomes: An update. Journal of Nutritional Science.
Setchell, K. D. R., et al. (2011). Soy isoflavone phase II metabolism differs between rodents and humans: Implications for the effect on breast cancer risk. American Journal of Clinical Nutrition.
Wang, Y., et al. (2021). The association between soy-based food and soy isoflavone intake and the risk of gastric cancer: A systematic review and meta-analysis. Journal of the Science of Food and Agriculture.
Weng, K., et al. (2017). Soy food intake and risk of gastric cancer: A dose-response meta-analysis of prospective studies. Medicine.
Zhang, Q., et al. (2017). Phytoestrogens and risk of prostate cancer: An updated meta-analysis of epidemiologic studies. International Journal of Food Sciences and Nutrition.
Zhen, W. (2017). Tasting soy sauce, teaching culture: A case for experiential learning. Association for Asian Studies.