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Type 2 Diabetes

5 Foods and Drinks to Avoid If You’re Taking Januvia

Jonathan Santana, DOPatricia Pinto-Garcia, MD, MPH
Written by Jonathan Santana, DO | Reviewed by Patricia Pinto-Garcia, MD, MPH
Published on January 7, 2026

Key takeaways:

  • Januvia (sitaglipitin) is a medication used to treat Type 2 diabetes.

  • Januvia doesn’t interact with any foods. But there are still some foods and eating patterns you should avoid while taking Januvia. 

  • Limit sugary drinks, refined carbohydrates, and alcohol while taking Januvia. 

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Januvia (sitagliptin) is a medicine that can treat Type 2 diabetes. It works by raising levels of helpful hormones that make it easier for your body to keep blood sugar in a healthy range. 

Unlike some medications, Januvia doesn’t interact with any foods or drinks. This means there isn’t anything you absolutely can’t eat or drink while taking Januvia. 

But there are foods and drinks that can keep Januvia from working at its best. Here are five foods and drinks you should limit while taking Januvia so you can get the best results while taking this medication. 

1. Refined carbohydrates

Refined carbohydrates lack fiber and nutrients found in whole grains. Examples of refined carbohydrates include:

  • While bread

  • White rice

  • White pasta

  • Baked goods like cookies and cakes

  • Crackers

Your body digests refined carbohydrates very quickly. This makes your blood sugar rise quickly. Januvia helps your body manage changes in blood sugar after you eat. But blood sugar spikes are more difficult to control than the slower increases that happen after you eat complex carbohydrates, like those in whole grains.

Limiting refined carbohydrates makes it easier for Januvia to keep your blood sugar in a healthy range after you eat and throughout the day. 

2. Sugary drinks

It’s a good idea to avoid drinks that are high in sugar because they can raise your blood glucose. This makes it harder for Januvia to keep your blood sugar within a target range. 

Examples of sugary drinks include:

  • Soda

  • Energy drinks

  • Sweetened iced tea

  • Fruit juice

  • Sports drinks

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Experts recommend limiting your added sugar intake to 25 g to 36 g each day, but most people eat 2 to 3 times more than that. 

You don’t have to cut out sugar entirely to get the best results from Januvia. But it’s a good idea to stick to the recommended limits. You can check for added sugar in drinks by reading the nutrition labels on the packaging. 

3. High-glycemic vegetables

A healthy diet should be rich in whole fruits and vegetables. But not all vegetables affect your blood sugar the same way. Some vegetables have a high glycemic index, which means they raise your blood sugar fast. These include starchy vegetables like:

  • Potatoes

  • Peas

  • Yams

  • Sweet potatoes

Diabetes Type 2 medicationsCompare prices and information on the most popular Diabetes Type 2 medications.
  • Januvia
    sitagliptin
    $335.47Lowest price
  • Glucophage
    Metformin
    $9.00Lowest price
  • Riomet
    Metformin
    $96.40Lowest price

You want to avoid blood sugar spikes to help Januvia work as effectively as possible. This doesn’t mean you have to cut out starchy vegetables completely. But enjoy them in moderation and choose low-glycemic vegetables when possible. 

4. Alcohol

There’s no amount of alcohol that’s safe for your health. And that’s especially true when you’re taking Januvia. 

Januvia can trigger hypoglycemia (low blood sugar). This is rare. But if you have diabetes, alcohol increases your risk of hypoglycemia. You can lower your risk by not mixing Januvia and alcohol. 

You don’t need to avoid alcohol completely, but you should limit your intake, eat food while drinking, and avoid sugary mixed drinks.

5. Garlic supplements

Garlic is a vegetable used to flavor many dishes. It has many potential health benefits and can help lower your blood sugar. This can be a good thing if you have diabetes. But too much garlic can also increase your risk of hypoglycemia. 

You have to eat a lot of garlic to trigger hypoglycemia. And most people won’t eat that much in one sitting. So, it’s safe to keep eating your favorite garlicky foods. 

But it’s easy to get too much garlic from concentrated products like garlic supplements. Avoid garlic supplements and other concentrated forms of garlic if you’re taking Januvia.

Frequently asked questions

Januvia may cause mild side effects, like diarrhea or an upset stomach. These symptoms can sometimes be confused with reactions to certain foods. People taking Januvia should avoid a strict ketogenic diet, because drastically reducing carbs can lead to dangerously low blood sugar.

Vitamin D doesn’t interact with Januvia. It’s safe to take both at the same time.

Januvia can be taken at any time of day, with or without food. Try to take your medication at the same time each day. This helps Januvia work best.

The bottom line

Januvia is a medication that can help manage Type 2 diabetes. It doesn’t interact with any food or drinks. But certain foods and drinks can stop Januvia from working at its best. Try to limit foods that cause blood sugar spikes while taking Januvia. This includes refined carbohydrates, sugary drinks, and high-glycemic (starchy) vegetables. You should also limit alcohol and avoid garlic supplements, as these can increase your risk of hypoglycemia (low blood sugar) while taking Januvia. 

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Why trust our experts?

Jonathan Santana, DO, is a board-certified and fellowship-trained pediatrician, with board certification in primary-care sports medicine. He has been in academic practice for 8 years as an assistant professor in orthopedics.
Patricia Pinto-Garcia, MD, MPH, is a medical editor at GoodRx. She is a licensed, board-certified pediatrician with more than a decade of experience in academic medicine.

References

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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