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Vidaza

Vidaza Side Effects

Allison Baxley, PharmD, BCOPConnie Zheng, PharmD
Reviewed by Allison Baxley, PharmD, BCOP, Connie Zheng, PharmD
Last reviewed on February 21, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (up to 71%)
  • Low red blood cells (up to 70%)
  • Low platelets (up to 70%)
  • Vomiting (up to 54%)
  • Fever (up to 52%)
  • Constipation (up to 50%)
  • Low white blood cells (up to 66%)
  • Injection site redness or warmth (up to 43%)
  • Diarrhea (36%)
  • Bruising (up to 31%)
  • Trouble breathing (29%)
  • Small red skin spots (up to 24%)
  • Injection site pain (up to 23%)
  • Joint pain (22%)
  • Headache (22%)

Less Common Side Effects

  • Low white blood cells with fever
  • Stomach pain and swelling
  • Bleeding gums and mouth
  • Chest pain
  • Chills or shivering
  • Weakness
  • Pneumonia
  • Cough, sore throat, and other symptoms of an upper respiratory tract infection
  • Muscle pain
  • Dizziness
  • Anxiety
  • Trouble sleeping
  • Rash
  • Tiredness

Vidaza serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Liver damage: tiredness, loss of appetite, nausea or vomiting, dark urine, right-side stomach pain, easy bruising or bleeding, or yellowing of the eyes or skin
  • Kidney damage: blood in urine, changes in urination (more or less)
  • High uric acid and electrolyte imbalances: dark urine, not urinating as much as usual, pain on either side of the lower back, racing heart, muscle cramps or spasms, numbness, nausea, vomiting
  • Serious bleeding: unusual bleeding, easy bruising, blood in urine or stool, confusion, vision changes
  • Serious infections: fevers, chills, sweating, trouble breathing

Source: DailyMed

The following Vidaza side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Black, tarry stools

bladder pain

bleeding gums

blood in the urine or stools

cloudy urine

body aches or pain

burning or stinging of the skin

chest pain

chills

congestion

cough

difficult breathing

difficulty swallowing

dizziness

ear congestion

fast heartbeat

fever

frequent urge to urinate

headache

hives, itching, or skin rash

hoarseness

loss of voice

lower back or side pain

muscle aches

nasal congestion

nausea

pain or tenderness around the eyes and cheekbones

painful cold sores or blisters on the lips, nose, eyes, or genitals

painful or difficult urination

pain, redness, swelling, tenderness, warmth on the skin

pale skin

pinpoint red spots on the skin

puffiness or swelling of the eyelids or around the eyes, face, lips or tongue

rapid heartbeat

runny nose

sneezing

sore throat

sores, ulcers, or white spots on lips or in mouth

stuffy nose

swollen glands

tender, swollen glands in the neck

tightness in the chest

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

voice changes

vomiting

Less common

Change in consciousness

convulsions

decreased urine

drowsiness

dry mouth

increased thirst

irregular heartbeat

loss of appetite

mood changes

muscle pain or cramps

numbness or tingling in the hands, feet, or lips

loss of consciousness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Diarrhea

nausea

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

appetite decreased

belching

bleeding after defecation

bloody nose

blurred vision

bruise

bumps on the skin

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

burning while urinating

diarrhea

difficulty having a bowel movement (stool)

difficulty with moving

discouragement

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

dry skin

fainting

fear

feeling of discomfort or illness

feeling of sluggishness

feeling sad or empty

feeling unusually cold

flushing

full or bloated feeling or pressure in the stomach

heartburn

heart murmur

indigestion

inflamed tissue from infection at the injection site

injection site bruising

irritability

itching at injection site

joint pain

lack of appetite

large, flat, blue or purplish patches in the skin

loss of interest or pleasure

mouth hemorrhage

muscle stiffness

nervousness

night sweats

pain in the joints

postnasal drip

post procedural hemorrhage

redness of the skin

shivering

small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope

small lumps under the skin

small red or purple spots in the mouth

soreness or discomfort to touch or pressure on the stomach

stomach discomfort upset or pain

sweating

swelling of abdominal or stomach area

swelling of the hands, ankles, feet, or lower legs

swelling or inflammation of the mouth

swelling with pits or depressions visible on the skin

swollen joints

tongue ulceration

trouble concentrating

trouble sleeping

uncomfortable swelling around the anus

unusual drowsiness

unusually warm skin

upper abdominal or stomach pain

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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