Decitabine Side Effects
What should I watch for?
Visit your doctor for checks on your progress. This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Do not become pregnant while taking this medicine or for at least 1 month after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for at least 2 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Black, tarry stools
bleeding after defecation
blood in urine or stools
bloody or cloudy urine
blue lips and fingernails
body aches or pain
coughing that sometimes produces a pink frothy sputum
difficult, burning, or painful urination
difficult, fast, noisy breathing, sometimes with wheezing
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
dryness of throat
fast or irregular heartbeat
feeling unusually cold
flushed, dry skin
frequent urge to urinate
fruit-like breath odor
hives or welts
loss of appetite
lower back or side pain
mood or mental changes
muscle pain or cramps
muscle spasms or twitching
nausea or vomiting
numbness or tingling in hands, feet, or lips
pinpoint red spots on skin
redness or pain at the catheter site
shortness of breath
small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope
small red or purple spots on skin, lips or in mouth
sore mouth or tongue
sores, ulcers, or white spots on lips or in mouth
swelling of face, hands, ankles, feet, or lower legs
swollen, painful, or tender lymph glands in neck, armpit, or groin
tightness in chest
trouble in swallowing
troubled breathing with exertion
uncomfortable swelling around anus
unexplained weight loss
unusual bleeding or bruising
unusual tiredness or weakness
weakness or heaviness of legs
white patches in mouth and/or on tongue
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Acid or sour stomach
bumps on skin
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
hair loss, thinning of hair
pain in arms or legs
pain in joints
stomach discomfort or upset
swelling or inflammation of the mouth
unable to sleep
unusual drowsiness, dullness, or feeling of sluggishness
Difficulty in moving
general feeling of discomfort or illness
pain in the tongue
pressure in the stomach
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.