The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Pain (85%)
- Fever (72%)
- Lower blood cell counts (up to 66%)
- Infusion reactions (60%)
- Low blood pressure (60%)
- Changes in liver labs (56%)
- Vomiting (46%)
- Diarrhea (43%)
- Lower electrolyte levels in the blood (up to 43%)
- Capillary leak syndrome (40%)
- Hives (37%)
- Low oxygen levels (24%)
Less Common Side Effects
- Swelling
- Bleeding
- High blood pressure
- Nausea
- Fast heartbeat
- Infections
- Peripheral neuropathy
- Weight gain
- Less appetite
Unituxin serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious infusion-related reactions: Hives, low blood pressure, lip and face swelling, breathing problems, wheezing, weakness, dizziness, chest pain, rash, flushing
- Posterior reversible encephalopathy syndrome (PRES): Severe headaches, seizures, confusion, changes in vision, difficulty staying awake, trouble speaking
- Transverse myelitis: Weakness in the legs or arms, back pain, tingling or numbing feelings, more frequent need to urinate, and constipation
- Dangerously low blood pressure: Dizziness, fainting, blurry vision, nausea, weakness, lightheaded
- Capillary leak syndrome: Unusual weakness or fatigue, feeling faint or lightheaded, less urine, swelling of the ankles, hands, or feet, or trouble breathing, low blood pressure
- Severe infections: Fevers, chills or sweats, shortness of breath, or fast heartbeat
Source: DailyMed
The following Unituxin side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Capillary leak syndrome—stomach or muscle pain, unusual weakness or fatigue, feeling faint or lightheaded, decrease in the amount of urine, swelling of the ankles, hands, or feet, trouble breathing
- Dilated pupils
- Eye pain, change in vision, vision loss
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
- Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
- Low calcium level—muscle pain or cramps, confusion, tingling, or numbness in the hands or feet
- Low potassium level—muscle pain or cramps, unusual weakness or fatigue, fast or irregular heartbeat, constipation
- Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
- Low sodium level—muscle weakness, fatigue, dizziness, headache, confusion
- Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
- Stomach pain, bloody diarrhea, pale skin, unusual weakness or fatigue, decrease in the amount of urine, which may be signs of hemolytic uremic syndrome
- Sudden and severe headache, confusion, change in vision, seizures, which may be signs of posterior reversible encephalopathy syndrome (PRES)
- Trouble passing urine
- Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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