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Tiopronin

Tiopronin Side Effects

Ashley Wong, PharmDAllison Gourley, PharmD
Reviewed by Ashley Wong, PharmD, Allison Gourley, PharmD
Last reviewed on September 9, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (12–25%)
  • Diarrhea or soft stools (6–18%)
  • Canker sores (12–18%)
  • Fatigue (14%)
  • Rash (12–14%)
  • Joint paint (12%)
  • Weakness (4–12%)
  • Vomiting (10%)
  • Protein in your urine (6–10%)
  • Fever (8%)

Less Common Side Effects

  • Allergic reactions that can cause fever, rash, joint pain, and swollen lymph nodes
  • Loss of appetite (8%)
  • Chest pain (6%)
  • Swelling (6%)
  • Bruising (6%)
  • Wrinkly skin (6%)
  • Stomach pain (6%)
  • Trouble getting an erection (6%)
  • Cough (6%)
  • Itching (4–6%)
  • Low red blood cell count (2–6%)

Source: DailyMed

The following Tiopronin side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet

Side effects that usually do not require medical attention (Report these to your care team if they continue or are bothersome.):

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