The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Endometriosis:
- Hot flashes (90%)
- Lower sex drive (20-25%)
- Vaginal dryness (15-20%)
- Headaches (15-20%)
- Mood swings (15-20%)
- Acne (15-20%)
Early puberty:
- Acne (10%)
- Temporarily larger breast size (8%)
- Vaginal bleeding (8%)
- Mood swings (6%)
- Temporary increase in pubic hair growth (5%)
- Runny nose (5%)
Less Common Side Effects
Endometriosis:
- Nasal irritation
- Muscle pain
- Smaller breast size
- Swelling in the hands or ankles
- Sweating
- Excessive growth of facial or body hair
- Weight gain or weight loss
- Depression
- Trouble sleeping
Early puberty:
- Body odor
- Sweating
- Hot flashes
- White or brownish vaginal discharge
Source: DailyMed
The following Synarel side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
For adults (female)
Breast enlargement
light vaginal bleeding between regular menstrual periods, called spotting
longer or heavier menstrual periods
vaginal bleeding between regular menstrual periods, called breakthrough bleeding
For children (male)
Body odor
growth of pubic hair
Less common or rare
Incidence not known
For adults (female)
difficulty with speaking
dizziness or lightheadedness
double vision
fainting
fast heartbeat
inability to move the arms, legs, or facial muscles
inability to speak
pain or discomfort in the arms, jaw, back, or neck
pain, redness, or swelling in the arm or leg
slow speech
sweating
troubled breathing
vomiting
yellow eyes or skin
Incidence not known
Anxiety or mental depression
changes in vision
cold, clammy, or pale skin
confusion
convulsions
headache
irregular heartbeats
nightmares or unusually vivid dreams
slow heart rate
vomiting
weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
For adults (female)
dandruff
increase or decrease in sexual desire
increased hair growth, often abnormally distributed
mood swings
oily skin
pain during sexual intercourse
rapid weight gain
reduced breast size
stopping of menstrual periods
swelling of the feet or lower legs
vaginal dryness
Less common or rare
For adults (female)
Breast pain
headache (mild and transient)
irritated or runny nose
mental depression (mild and transient)
For children (male)
Irritated or runny nose
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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