The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
3.75 mg:
- Hot flashes (59%)
- Bone pain (12%)
- Erectile dysfunction (7%)
11.25 mg:
- Hot flashes (73%)
- Bone pain (13%)
- Headache (7%)
22.5 mg:
- Hot flashes (73%)
- Flu infection (16%)
- High blood pressure (14%)
- Urinary tract infection (12%)
- Back pain (11%)
- Erectile dysfunction (10%)
Less Common Side Effects
3.75 mg:
- Headache
- Tiredness
- Dizziness
- Diarrhea
- Trouble sleeping
11.25 mg:
- Pain at the injection site
- Dizziness
- Nausea
- Swelling in the legs
- Erectile dysfunction
- Painful urination
22.5 mg:
- Swelling in the arms and legs
- Bronchitis
- Rise in blood sugar
- Joint pain
- Headache
- Trouble sleeping
- Trouble urinating
Trelstar serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: rash, swelling of the face or throat, trouble breathing
- Heart attack: chest pain, shortness of breath, rapid breathing, sweating, fatigue, dizziness, nausea, vomiting
- Heart rhythm problems: fast or uneven heartbeat, fainting, dizziness
- Stroke: sudden numbness or weakness, confusion, trouble talking, trouble seeing, dizziness, trouble walking
- Seizure: sudden jerking or shaking, loss of consciousness, confusion, trouble speaking
Source: DailyMed
The following Trelstar side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Less common
For children
body aches or pain
chills
cough producing mucus
difficulty with breathing
ear congestion
general feeling of discomfort or illness
headache
joint pain
loss of voice
mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness
muscle aches and pains
shivering
sweating
tightness in the chest
trouble sleeping
unusual tiredness or weakness
vomiting
For adult men
Bladder pain
bloating or swelling of the face, arms, hands, lower legs, or feet
bloody or cloudy urine
blurred vision
cough producing mucus
decrease in urine volume or frequency of urination
difficult or labored breathing
difficult, burning, or painful urination
difficulty in passing urine
dizziness
flushed, dry skin
frequent urge to urinate
fruit-like breath odor
headache
increased hunger
increased thirst
increased urination
loss of consciousness
lower back or side pain
nervousness
pale skin
pounding in the ears
rapid weight gain
slow or fast heartbeat
stomach ache
sweating
tightness in the chest
tingling of the hands or feet
troubled breathing
troubled breathing with exertion
unexplained weight loss
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight gain or loss
vomiting
Incidence not known
For children
Blurred or loss of vision
difficulty with swallowing
disturbed color perception
dizziness
double vision
halos around lights
nervousness
night blindness
overbright appearance of lights
pounding in the ears
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
seizures
slow or fast heartbeat
thoughts of killing oneself
For adult men
changes in skin color
changes in vision
chest discomfort
cold, clammy, or pale skin
confusion
dizziness or lightheadedness
fainting
inability to speak
irregular heartbeat
numbness or tingling in the face, arms, or legs
pain or discomfort in the arms, jaw, back, or neck
pain, redness, or swelling in the arm or leg
seizures
severe or sudden headache
slow heart rate
slurred speech
sudden shortness of breath or troubled breathing
temporary blindness
tenderness
trouble speaking, thinking, or walking
weakness in the arm or leg on one side of the body, sudden and severe
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
For children
Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
stuffy or runny nose
For adult men
Bone pain
chills
decrease in testicle size
decreased interest in sexual intercourse
feeling of warmth or redness of the face, neck, arms, and occasionally, upper chest
general feeling of discomfort or illness
inability to have or keep an erection
joint pain
leg pain
loss in sexual ability, desire, drive, or performance
loss of appetite
muscle aches and pains
redness of the face, neck, arms, and occasionally, upper chest
shivering
sudden sweating
trouble sleeping
Less common
For children
Change in hearing
dryness or soreness of the throat
ear drainage
hoarseness
itching of the ears
pain or tenderness around the eyes and cheekbones
tender, swollen glands in the neck
voice changes
For adult men
Back pain
belching
body aches or pain
breast pain
burning, dry, or itching eyes
congestion
crying
depersonalization
difficulty having a bowel movement
difficulty with moving
discharge or excessive tearing
dysphoria
euphoria
hoarseness
indigestion
injection site pain
itching or rash
lack or loss of strength
leg cramps
loss of appetite
muscle aching or cramping
muscle pains or stiffness
paranoia
quick to react or overreact emotionally
rapidly changing moods
redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
stomach discomfort, upset, or pain
swelling of the breasts or breast soreness in both females and males
swollen joints
tender, swollen glands in the neck
trouble swallowing
voice changes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

