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Sulindac Coupon - Sulindac 200mg tablet

sulindac

Generic Clinoril
Used for Rheumatoid Arthritis, Osteoarthritis, Gout
Used for Rheumatoid Arthritis, Osteoarthritis, Gout

Sulindac works well to treat pain and swelling in different types of arthritis and in certain shoulder injuries. Sulindac should be used at the lowest dose possible for the shortest duration of time to manage your symptoms. That's because it can cause serious side effects, such as stroke, heart attack, and stomach bleeds.

Last reviewed on November 14, 2021
basics-icon

What is Sulindac?

What is Sulindac used for?

  • Osteoarthritis

  • Rheumatoid arthritis

  • Arthritis of the spine (ankylosing spondylitis)

  • Gout (gouty arthritis)

  • Sharp shoulder pain (acute subacromial bursitis and supraspinatus tendinitis)

How Sulindac works

Sulindac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking proteins in your body that cause pain and swelling.

Drug Facts

Common BrandsClinoril (brand no longer available)
Drug ClassNSAID
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$39.10(save 57.26%)
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$16.71
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What are the side effects of Sulindac?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Stomach pains (10%)
  • Heartburn (3-9%)
  • Nausea (3-9%)
  • Diarrhea (3-9%)
  • Constipation (3-9%)
  • Rash (3-9%)
  • Dizziness (3-9%)
  • Headache (3-9%)

Other Side Effects

  • Passing gas
  • Stomach cramps
  • Itchy and dry skin
  • Nervousness
  • Ringing in the ear
  • Swelling of the arms and legs

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Heart attack: dizziness, tiredness, cold sweat, trouble breathing, chest pain or tightness, anxiety
  • Stroke: tiredness, lightheadedness, blurred vision, difficulty speaking, difficulty walking, weakness on one side of the body
  • Stomach bleeds: blood in your vomit, stool that looks like black coffee grounds, pain in your stomach that doesn't go away
  • Heart failure: trouble breathing, tiredness, swelling in your body, sudden weight gain
  • Kidney damage: nausea, vomiting, tiredness, loss of appetite, changes in how much you urinate
  • Liver damage: fever, chills, fatigue, nausea, vomiting, yellowing of the skin or whites of the eyes, clay-colored stool, and dark urine
  • Severe asthma attack: chest pain, cough, difficulty breathing, wheezing
  • Serious allergic and skin reaction: fever, rash, body aches, cough, swelling of the face, peeling skin, painful blisters all over your body

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Acid or sour stomach

belching

constipation

headache

heartburn

nausea or vomiting

skin rash

stomach pain

Less common

Excess air or gas in the stomach or intestines

itching skin

passing gas

stomach cramps

swelling

weight loss

Rare

Back or leg pains

bleeding gums

blistering, peeling, or loosening of the skin

bloating

bloody or black, tarry stools

bloody or cloudy urine

blurred or loss of vision

burning feeling in the chest or stomach

burning while urinating

chest pain

chills

clay-colored stools

confusion

cough or hoarseness

cracks in the skin

dark urine

decreased urine output

diarrhea

difficult or labored breathing

difficult or painful urination

difficulty with swallowing

dilated neck veins

discoloration of urine

disturbed color perception

dizziness

double vision

extreme fatigue

eye pain

fainting

feeling of warmth

fever

flu-like symptoms

general body swelling

general feeling of discomfort or illness

groin pain

halos around lights

hives

increased sensitivity of the skin to sunlight

increased sweating

increased thirst

indigestion

irregular breathing

joint or muscle pain

large, flat, blue, or purplish patches in the skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

light-colored stools

loss of appetite

loss of heat from the body

lower back or side pain

muscle aches, pains, or weakness

nervousness

night blindness

noisy breathing

nosebleeds

numbness or tingling in the hands, feet, or lips

overbright appearance of lights

painful or difficult urination

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

persistent bleeding or oozing from puncture sites, mouth, or nose

pinpoint red or purple spots on the skin

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

red, irritated eyes

redness of the face, neck, arms and occasionally, upper chest

redness or other discoloration of the skin

redness, swelling, or soreness of the tongue

scaly skin

seizures

severe or continuing stomach pain

severe sunburn

shortness of breath

slow or fast, irregular, pounding, or racing heartbeat or pulse

sore throat

sores, ulcers, or white spots in the mouth or on the lips

stiff neck or back

stomach upset

swelling of the face, fingers, feet, or lower legs

swelling or inflammation of the mouth

swollen or painful glands

tenderness in the stomach area

tightness in the chest

troubled breathing

tunnel vision

unpleasant breath odor

unusual bleeding or bruising

unusual tiredness or weakness

upper right abdominal pain

vomiting of blood or material that looks like coffee grounds

watery or bloody diarrhea

weakness or heaviness of the legs

weight gain

wheezing

yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Change in consciousness

decreased awareness or responsiveness

loss of consciousness

severe sleepiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Continuing ringing or buzzing or other unexplained noise in the ears

hearing loss

Rare

Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

burning, dry, or itching eyes

decreased hearing

difficulty with moving

discharge, excessive tearing

discouragement

false sense of well-being

feeling of constant movement of self or surroundings

feeling sad or empty

hair loss or thinning of the hair

hallucinations

irritability

loss of interest or pleasure

metallic or bitter taste

mood swings

muscle cramping or stiffness

personality changes

redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

restlessness

sensation of spinning

sleepiness or unusual drowsiness

sleeplessness

sore or dry mucous membranes

swelling or redness in the joints

trouble with concentrating

trouble with sleeping

unable to sleep

vaginal bleeding

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Sulindac

thumbs-up

Pros

Available as a less expensive generic medication

Works well to lower pain and inflammation

Lasts longer than some other NSAIDs, so you only need to take it twice daily

thumbs-down

Cons

Can cause stomach bleeding or stomach ulcers

Not recommended for use starting the second trimester of pregnancy or later

Not a good option for people with certain conditions, such as heart problems, history of stroke, or kidney problems

pharmacist-tips

Pharmacist tips for Sulindac

pharmacist
  • Sulindac helps lower your pain and swelling, but it won't prevent your condition from getting worse. Depending on the cause of your pain, there might be things you can do to prevent it from getting worse. These include physical therapy, exercise, or taking other medications. Discuss with your provider to see what the best options are for you.

    • Sulindac can cause rare, but potentially life-threatening skin reactions. If you notice fever, body aches, cough, peeling skin, and painful blisters all over your body (especially on the skin around the eyes, mouth, throat, or genitals), stop sulindac and talk to your healthcare provider right away.

      • Sulindac can cause stomach bleeds, a very serious side effect. Symptoms of stomach bleeds include blood in your vomit, stool that looks like black coffee grounds, and pain in your stomach that doesn't go away. If you experience these symptoms, get medical help right away.

        • Sulindac can cause anemia (low red blood cell levels). Let your provider know if you experience symptoms of anemia, such as feeling tired or weak, having pale skin, trouble breathing, or cold hands and feet.

          • It's not recommended to take sulindac with other NSAIDs, such as ibuprofen (Advil) or naproxen (Aleve). Doing so puts you at higher risk for stomach bleeds, stroke, and heart attack. NSAIDs are commonly found in over-the-counter and prescription pain and cold medications. Talk with your healthcare provider or pharmacist if you're not sure whether you're already taking an NSAID.

            faqs

            Frequently asked questions about Sulindac

            What is the difference between osteoarthritis, rheumatoid arthritis, gouty arthritis, and ankylosing spondylitis?
            Arthritis is a condition where there's swelling, stiffness, and pain at the joints. Osteoarthritis, rheumatoid arthritis, gouty arthritis, and ankylosing spondylitis are different types of arthritis. While they share some similar symptoms, they develop differently in your body. Osteoarthritis happens when your cartilage, the "cushion" between your joints, wears out over time and your bones rub against each other. Rheumatoid arthritis occurs when your body's own immune system, which works to protect you from infections, attacks your joints instead. Gouty arthritis (gout) happens when there's too much uric acid in your body and it forms crystals in your joints, typically starting in the big toe. Ankylosing spondylitis is arthritis that mainly affects the joints along the spine. Healthcare providers don't treat these conditions the same. But sulindac can lower joint pain and swelling in all four conditions.
            What is sharp shoulder pain (acute subacromial bursitis and supraspinatus tendinitis)?
            Sharp shoulder pain (acute subacromial bursitis and supraspinatus tendinitis) is pain and swelling in the rotator cuff area of your shoulder. The rotator cuff connects your arm to your shoulder. It helps you move, rotate, and raise your arm. Subacromial bursitis is a sharp, painful swelling of a fluid sac in your rotator cuff. This sac normally helps to cushion your shoulder joint so your arm can move and rotate smoothly. Supraspinatus tendinitis is a painful swelling of a tendon in the rotator cuff. Both these conditions are commonly seen in athletes who do a lot of overhead movements, such as pitching in baseball, playing golf, and swimming. Sulindac can be used in both types of rotator cuff injury to lower pain and swelling.
            Why does sulindac have so many potential side effects?
            Sulindac works by blocking proteins called cyclooxygenase 1 and 2 (COX-1 and COX-2) enzymes from making prostaglandins. Prostaglandins are chemicals that have many roles in your body. When you get a cut or bruise, these chemicals can cause pain and swelling at the location of your injury. They also protect your gut from stomach acid, help your kidneys work normally, and balance blood flow throughout your body. When you take sulindac, you're not only preventing prostaglandins from causing pain and swelling, you're blocking them from working in other parts of your body as well. That's why taking sulindac puts you at risk for certain side effects, such as stomach pain, kidney damage, stroke, and heart attack.
            Can I take sulindac and ibuprofen (Advil) at the same time?
            Taking both sulindac and ibuprofen (Advil) is typically not recommended. These medications are NSAIDs and taking them together can raise your risk of serious side effects, such as stroke, heart attack, and stomach bleeds. If your current dose of sulindac is not enough to control your pain, talk to your provider to see what other options are good for you.
            Can I take sulindac and acetaminophen (Tylenol) at the same time?
            It's possible to take sulindac and acetaminophen (Tylenol) together because they work differently to ease your pain. Discuss with your provider to see if taking both medications together is a possible option for you.
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            warings-icon

            What are the risks and warnings for Sulindac?

            Sulindac can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Heart attack and stroke

            • Risk factors: History of heart problems | History of heart bypass surgery | Taking higher doses of sulindac | Taking sulindac for a long time

              Sulindac can raise your risk of having blood clots, heart attacks, or strokes. This can happen as early as within the first weeks of starting this medication. People with heart problems, those taking higher doses of sulindac, and those taking sulindac for a long time are at greater risk for these side effects. That’s why it’s important to take the lowest possible dose for the shortest possible time. If you have heart problems, talk to your healthcare provider before starting this medication. Don't take sulindac if you've had or will be having heart bypass surgery. Call 911 or seek immediate medical help if you experience chest pain, trouble breathing, weakness on one side of your body, or trouble speaking or walking.

              risk-warning

              Stomach bleeding and ulcers

              • Risk factors: History of stomach bleeding or ulcers | Older adults | Taking aspirin (Aspir-Low), other NSAIDs, corticosteroids, or blood thinners | Drinking alcohol | Smoking | Having poor health | Taking sulindac for a long time | Taking higher doses of sulindac

                Sulindac can cause stomach bleeding and ulcers. It can also make it more difficult for your body to form blood clots, which can be dangerous. There are many conditions and medications that raise your risk of these problems, so speak with your provider before starting this medication. Stomach bleeding and ulcers can occur without warning or symptoms, so it's best to take the lowest possible dose for the shortest possible time to minimize your risk. If you take sulindac for a long time, you might need to get regular lab work to check if you have any bleeding inside your body. If you notice blood in your vomit, stool that looks like black coffee grounds, or if you have pain in your stomach that doesn't go away, stop this medication and talk to your healthcare provider right away.

                risk-warning

                High blood pressure, heart failure, and swelling of your arms and legs

                • Risk factors: History of high blood pressure | History of heart failure

                  Sulindac can make it more difficult for your kidneys to pass urine. This can raise your blood pressure, and it can also cause your body to hold onto more water. Over time, this might lead to new or worsen existing blood pressure problems, heart failure, and swelling of your arms and legs. Sulindac can also interact with certain medications used to treat these conditions, such as furosemide (Lasix), lisinopril (Zestril), and losartan (Cozaar). Monitor your blood pressure closely when you take sulindac. It's not recommended to use sulindac if you have heart failure, unless the benefit of this medication is greater than the risk of side effects. Let your provider know right away if you notice any changes in your blood pressure or experience symptoms such as trouble breathing, tiredness, swelling in your body, or sudden weight gain.

                  risk-warning

                  Liver damage

                  • Risk factors: History of liver damage | Taking high doses of sulindac

                    Very rarely, sulindac can cause life-threatening liver damage. Your dose might be lower if you already have a history of liver damage. Talk to your healthcare provider right away if you experience symptoms, such as fever, chills, fatigue, nausea, vomiting, stomach pain, yellowing of the skin or whites of the eyes, clay-colored stool, and dark urine, you might need to stop this medication.

                    risk-warning

                    Kidney problems

                    • Risk factors: Older adults | Taking sulindac for a long time | Kidney problems | Heart failure | Liver problems | Loss of body fluid through conditions such as severe vomiting, bleeding, or diarrhea | Taking certain high blood pressure medications, such as water pills and ACEIs

                      Sulindac can damage your kidneys by slowing down blood flow to the kidneys. The risk is higher if you take this medication for a long time, take certain blood pressure medications (like ACEIs or water pills), or have certain conditions (like kidney or liver problems). This medication isn't recommended if you have very severe kidney problems, so discuss the risks and benefits of taking it with your provider. Your dose might be lower if you have a history of kidney damage. Let your healthcare provider know if you notice a change in how often you urinate after starting sulindac. Kidney damage usually goes away once you stop taking this medication.

                      Very rarely, sulindac causes kidney stones. Symptoms of kidney stones include sharp pain on either side of your lower back, nausea, vomiting, and blood in the urine. If you have a history of kidney stones, remember to drink water and keep hydrated while taking this medication. This will lower your risk of getting more stones.

                      risk-warning

                      Swelling in the pancreas

                      Sulindac can cause pancreatitis, a swelling of the pancreas. If you experience symptoms of pancreatitis, such as pain that starts in your stomach and spreads to your back, nausea, vomiting, and fever, stop this medication and get medical help right away.

                      risk-warning

                      Severe asthma attack

                      • Risk factors: Asthma and stuffy nose with or without nasal polyps | Allergic reaction to aspirin

                        Sulindac can cause your airways to tighten, which might lead to severe asthma attacks. Be careful using this medication if you have asthma. People who have experienced asthma attacks triggered by aspirin (Aspir-Low) or other NSAIDs in the past should avoid sulindac. Call 911 right away if your throat tightens and you can't breathe.

                        risk-warning

                        Severe allergic and skin reaction

                        Sulindac might cause sudden and very serious skin reactions, such as Stevens-Johnson syndrome (SJS). Symptoms include fever, body aches, cough, peeling skin, and painful blisters all over your body (especially the skin around the eyes, mouth, throat, or genitals). This medication might also cause drug reaction with eosinophilia and systemic symptoms (DRESS). Early signs of DRESS include fever and swollen lymph nodes. Lymph nodes are small groups of glands located in areas such as the neck and armpits. Symptoms of DRESS can also include rash, swelling of the face, and in severe cases, multiple organ damage. Stop the medication and get medical help right away at the earliest signs of serious allergic and skin reactions.

                        risk-warning

                        Harm to unborn babies

                        • Risk factors: Currently pregnant

                          If sulindac is taken during or after the second trimester of pregnancy, it can lower the amniotic fluid (the fluid that surrounds the baby in the womb). This can occur as soon as 2 days after starting the medication and result in serious kidney problems in your unborn baby. Babies born to mothers who take sulindac starting the third trimester of pregnancy or later can also develop heart problems. This medication is typically not used in pregnancy unless the benefit is greater than the risk of side effects and harm to the unborn baby. Talk to your provider if you're thinking of getting pregnant or become pregnant while taking sulindac.

                          dosage

                          Sulindac dosage forms

                          The average cost for 60 tablets of 200mg of Sulindac is $18.03 with a free GoodRx coupon. This is 53.89% off the average retail price of $39.10.
                          tablet
                          Tablet
                          DosageQuantityPrice as low asPrice per unit
                          150mg60 tablets$16.71$0.28
                          200mg60 tablets$18.03$0.30

                          Typical dosing for Sulindac

                          Your dose might differ depending on your individual treatment needs, and on whether you have liver or kidney problems.

                          • Osteoarthritis: The typical dose starts at 150 mg by mouth twice daily with food. The maximum daily dose is 400 mg.

                          • Rheumatoid arthritis: The typical dose starts at 150 mg by mouth twice daily with food. The maximum daily dose is 400 mg.

                          • Arthritis of the spine (ankylosing spondylitis): The typical dose starts at 150 mg by mouth twice daily with food. The maximum daily dose is 400 mg.

                          • Gout (gouty arthritis): The typical dose is 200 mg by mouth twice daily with food. The maximum daily dose is 400 mg. Treatment usually lasts 7 days.

                          • Sharp shoulder pain (acute subacromial bursitis/supraspinatus tendinitis): The typical dose is 200 mg by mouth twice daily with food. The maximum daily dose is 400 mg. Treatment usually lasts 7-14 days.

                          interactions

                          Interactions between Sulindac and other drugs

                          Sulindac may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Sulindac. Please note that only the generic name of each medication is listed below.

                          Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                          Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                          Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                          drug-cost

                          How much does Sulindac cost?

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                          contraindications-icon

                          Sulindac contraindications

                          Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Sulindac will not be safe for you to take.
                          • Asthma, hives, or allergic reactions after taking aspirin (Aspir-Low) or other NSAIDs

                          • Heart bypass surgery

                          alternatives

                          What are alternatives to Sulindac?

                          There are a number of medications that your doctor can prescribe in place of Sulindac. Compare a few possible alternatives below.
                          Sulindac
                          Used for:
                          • Osteoarthritis

                          • Rheumatoid arthritis

                          • Arthritis of the spine (ankylosing spondylitis)

                          • Gout (gouty arthritis)

                          • Sharp shoulder pain (acute subacromial bursitis and supraspinatus tendinitis)

                          $16.71 Lowest GoodRx priceView Prices
                          Used for:
                          • Mild to moderate pain

                          • Osteoarthritis

                          • Rheumatoid arthritis

                          • Ankylosing spondylitis (arthritis of the spine)

                          • Migraine attacks

                          • Menstrual cramps

                          $13.20 Lowest GoodRx priceView Prices
                          images

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                          This medicine is Yellow, Oval, Scored Tablet Imprinted With "E 11".Yellow Oval E 11 - Sulindac 200mg Tablet
                          Yellow Round Mp 116 - Sulindac 200mg Tablet
                          This medicine is Yellow, Round, Scored Tablet Imprinted With "Mp 116".Yellow Round Mp 116 - Sulindac 200mg Tablet

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