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Desmopressin Coupon - Desmopressin 0.2mg tablet

desmopressin

Generic Stimate
Used for Bed Wetting, Diabetes Insipidus, Hemophilia, Von Willebrand Disease

Desmopressin nasal spray treats problems relating to your body making too much urine (central diabetes insipidus). The medication comes as a nasal spray that you squirt into your nose.

Reviewed by:
reviewerAllison Gourley, PharmD
reviewerAshley Wong, PharmD
Last reviewed on November 24, 2021
basics-icon

What is Desmopressin nasal spray?

What is Desmopressin nasal spray used for?

  • Central diabetes insipidus (extreme thirst and frequent urination due to low vasopressin)

How Desmopressin nasal spray works

Desmopressin nasal spray is a synthetic vasopressin analog, which means it's a man-made form of a natural hormone in your body called vasopressin. It works in your kidneys to balance fluids in your body and stop you from making too much urine.

Drug facts

Common BrandsStimate(brand no longer available)
Drug ClassSynthetic Vasopressin Analog
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Desmopressin nasal spray

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache
  • Sore throat
  • Cough
  • Common cold
  • Nausea
  • Flushing
  • Mild stomach cramps

Less Common Side Effects

  • Sneezing
  • Stuffy nose
  • Nosebleed

Desmopressin nasal spray serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Less sodium in your body: seizures, coma, or death
  • Allergic reactions: trouble breathing, hives, swelling in your face, lips, tongue, or throat

Source: DailyMed

The following Desmopressin nasal spray side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Chills

confusion

cough

difficulty swallowing

dizziness

drowsiness

fever

puffiness or swelling of the eyelids or around the eyes

seizures

skin rash, hives, or itching

tightness in the chest

trouble breathing

unusual tiredness or weakness

Incidence not known

Blurred vision

body aches or pain

chest pain

decreased urine output

ear congestion

fast, irregular, pounding, or racing heartbeat or pulse

headache

increased thirst

loss of consciousness

loss of voice

muscle pain or cramps

nausea

nervousness

nosebleed

pounding in the ears

runny or stuffy nose

slow or fast heartbeat

sneezing

sore throat

swelling of the face, ankles, or hands

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Bloody nose

burning, dry, or itching eyes

diarrhea

eye discharge or excessive tearing

indigestion

loss of appetite

passing gas

redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

stomach pain, fullness, or discomfort

Incidence not known

Belching

feeling of warmth

heartburn

redness of the face, neck, arms, and upper chest

sleepiness or unusual drowsiness

stomach cramps

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Pros and cons of Desmopressin nasal spray

Pros

  • Good option for those who cannot take desmopressin tablets by mouth
  • Starts to work quickly, within minutes

Cons

  • Can cause dangerously low levels of sodium
  • Not a good treatment option if you have kidney problems
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Pharmacist tips for Desmopressin nasal spray

pharmacist
  • The desmopressin nasal spray pump must be primed before you use it for the first time. To prime the pump, press down four times to release the medication into the air. If the pump is not used for more than 1 week, re-prime it by pressing down on the pump once.
  • The bottle contains 50 sprays, not including the sprays you use while priming the bottle. Any medication remaining in the nasal spray bottle after 50 doses should be thrown away because you won't get the full 10 mcg of medication per spray.
  • Blow your nose before using desmopressin nasal spray so that your nose is clear and free of mucus that could block the medication.
  • If your provider prescribed one dose, put the tip of the spray into one nostril and administer one spray. If your provider prescribed two doses, administer one spray in each nostril.
  • Be sure to keep the desmopressin nasal spray bottle at room temperature; don't refrigerate it. Make sure to keep the bottle upright.
  • You should watch your child as they're using desmopressin nasal spray to make sure they get the full prescribed dose.
  • If you're taking desmopressin nasal spray for diabetes insipidus, your healthcare provider may want you to limit the fluids you drink.
faq-icon

Common questions about Desmopressin nasal spray

Most people, especially children and older adults, need to limit the amount of water or fluids they drink while taking desmopressin nasal spray. If you drink too much water while taking desmopressin nasal spray, it can cause you to have too much fluid in your body because the medication stops you from urinating as much. This can cause discomfort, headaches, dizziness, and low levels of salt (sodium) in your body. Your provider will let you know if you need to limit the fluids you drink.

Vasopressin, also known as anti-diuretic hormone, is a natural hormone that controls the amount of water in our body. Desmopressin nasal spray is the man-made version of vasopressin that works better to control urination and water balance in our bodies.

Sometimes, if you use desmopressin nasal spray for a long time, you might stop getting any benefit from it. If this happens, call your provider because they might need to raise your dose.

If you swallow desmopressin nasal spray, get medical help right away or call the poison control center at 1-800-222-1222. Swallowing even just a small amount of nasal spray can be harmful and cause serious side effects.

DDAVP, Stimate, and Noctiva are brand-name versions of desmopressin nasal spray. Each medication is used to treat different conditions. DDAVP is used to treat central diabetes insipidus, Stimate treats blood clotting disorders called Von Willebrand disease and mild hemophilia A, and Noctiva treats frequent overnight urination (nocturia). DDAVP and Stimate were voluntarily recalled by the manufacturer, Ferring Pharmaceuticals, in 2020 because they contained higher levels of desmopressin than specified, so they are not currently available. Noctiva was discontinued in the U.S. in 2019 because it wasn't used very much.

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Risks and warnings for Desmopressin nasal spray

Desmopressin nasal spray can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Low sodium levels

  • Risk factors: Children | Age 65 years or older | Having conditions that cause fluid and electrolyte problems such as heart failure or kidney disease | Taking other medications that cause low sodium levels

Desmopressin nasal spray can cause dangerously low sodium levels, which can lead to seizures, coma, respiratory arrest (can't breathe), or death. To lower your risk, your provider will likely have you limit the amount of fluids you drink and they will make sure your sodium levels are normal before you start desmopressin nasal spray. If you experience headache, nausea, vomiting, tiredness, weight gain, muscle weakness, cramps, or spasms, loss of appetite, or seizures, let your provider know right away.

Poor absorption

  • Risk factors: Abnormal nasal mucosa | Using desmopressin nasal spray for a long time

You shouldn't use desmopressin nasal spray if you have scarring in your nose, nasal blockages, or have recently had nasal surgery. These things can affect how much desmopressin nasal spray is absorbed in your body and the medication might not work for you. This can also happen if you've been taking desmopressin nasal spray for a long period of time. If this applies to you, your provider may prescribe another form of desmopressin nasal spray, like the oral or injectable form.

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Desmopressin nasal spray dosage

The average cost for 90 tablets of 0.2mg of Desmopressin nasal spray is $42.64 with a free GoodRx coupon. This is 84.73% off the average retail price of $279.16.
nasal sprayNasal spray
DosageQuantityPrice as low asPrice per unit
5ml of 0.01%1 nasal spray$51.44$51.44

Typical dosage for Desmopressin nasal spray

  • Adults: The typical starting dose is 10 mcg to 40 mcg into one nostril once a day, either given all at once or split into two or three doses throughout the day.
  • Children age 4 years and older: The typical starting dose is 10 mcg into one nostril daily. If your child's provider raises their dose, they might give it all at once or split the total daily dose into two doses (one dose in the morning and the other at nighttime).

Desmopressin nasal spray is also available as an injection in your veins and under your skin that is administered by a healthcare provider.

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Interactions between Desmopressin nasal spray and other drugs

Desmopressin nasal spray may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Desmopressin nasal spray. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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contraindications-icon

Desmopressin nasal spray contraindications

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Desmopressin nasal spray will not be safe for you to take.

  • Poor kidney function
  • Low sodium levels
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Desmopressin nasal spray images

White Round Hp 319 - Desmopressin Acetate 0.2mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "Hp 319".White Round Hp 319 - Desmopressin Acetate 0.2mg Tablet
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This medicine is White, Round, Scored Tablet Imprinted With "0.2".White Round 0.2 - Desmopressin Acetate 0.2mg Tablet
White Round S 72 - Desmopressin Acetate 0.2mg Tablet
This medicine is White, Round Tablet Imprinted With "S 72".White Round S 72 - Desmopressin Acetate 0.2mg Tablet
White Round Apo And Des 0.2 - Desmopressin Acetate 0.2mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "Des 0.2" And "Apo".White Round Apo And Des 0.2 - Desmopressin Acetate 0.2mg Tablet
White Oval 22 26 And Wpi - Desmopressin Acetate 0.2mg Tablet
This medicine is White, Oval, Scored Tablet Imprinted With "22 26" And "Wpi".White Oval 22 26 And Wpi - Desmopressin Acetate 0.2mg Tablet

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